Pharmacological interventions for alcohol relapse prevention
Journal Title: Internet Journal of Medical Update - Year 2015, Vol 10, Issue 2
Abstract
Alcohol dependence is a chronic, debilitating disorder that is an important public health problem worldwide. Combined psychological and pharmacological treatment packages produce best outcomes in its management. In this paper we discuss the three NICE – approved relapse prevention medications used in treatment of alcohol dependence: acamprosate, naltrexone and disulfiram. We review the pharmacological profile, mode of action, pharmacokinetics, and safety and tolerability of each of these pharmacological interventions. We discuss how each intervention can be used in clinical practice and review the efficacy of each drug. No one drug is clearly superior to the other, and clinical factors and patient choice should inform the choice of drug.
Authors and Affiliations
Anita Chithiramohan, Sanju George
Keywords
Related Articles
- EP ID EP296327
- DOI 10.4314/ijmu.v10i2.7
- Views 89
- Downloads 0
Necrotising fasciitis of breast
A clinical study on etiology, prognosis, outcome and role of endoscopy in upper gastrointestinal bleed in a tertiary care center
Upper gastrointestinal bleed is defined as bleeding proximal to the ligament of Treitz. The aim of this study was to know the cause of upper GI bleed, prognosis of the patients and role of upper gastrointestinal endoscop...
Touch Surgery™ - The Operating Room in your Pocket: a Surgical Simulation app Publisher: Touch Surgery Labs, 230 City Road, London, EC1V 2QY, UK Available for Android and iOS
None
Small group teaching and learning
None
Myoepithelial carcinoma of the male breast
None