Pharmacovigilance in Dermatology
Journal Title: International Journal of Allied Medical Sciences and Clinical Research - Year 2013, Vol 1, Issue 2
Abstract
Pharmacovigilance is the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other possible medicine-related problems. A huge quantity of adult people suffer from undesired side effects to pharmaceutical products at some stage in the way of their lives and can be classified as expected or A-type reactions and unexpected or B type reactions. The skin is a favoured target organ for B-type reactions and these skin reactions occur in 2–3% of hospitalized patients. Morbilliform drug rashes are the generally happening skin reactions to drugs, constituting up to 90% of all reactions, followed by drug induced urticaria, which constitutes about 6%. The Council for International Organization of Medical Sciences (CIOMS) considers as serious ADRs that are lethal or life-threatening, or need prolonged hospitalization or consequence in persistent or considerable disability or incapacity because hospitalization may depend on the socioeconomic status of the patient and on admittance to health care. The centre of attention of this summary is on pattern of cutaneous ADRs. Case evaluation must commence with a precise explanation of the skin lesions. The documentation of cases should be terminated by photographic pictures which can help for the retrospective evaluation of cases by experts. Concluded that, there is a need of active Pharmacovigilance centre with intensive monitoring for drug induced reactions in the dermatology department
Authors and Affiliations
Languluri Reddenna
Keywords
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