Phenotypic detection of ESBL among E.coli and Klebiella pneumoniae by modified CLSI guidelines
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2018, Vol 4, Issue 3
Abstract
Introduction Escherichia coli and Klebsiella pneumoniae cause a wide range of infections Multidrugresistance strains carrying resistance genes have become a growing problem worldwide The ESBLs have emerged distinctly especially in Escherichia coli and Klebsiella pneumoniaeMaterial and Methods 250 non repetitive isolates of E coli and K pneumoniae were isolated from different clinical samples pus urine sputum blood for the study Each isolate was tested for production of ESBL by CLSI recommended PCT and compared with Modified CLSI Method for ESBL detectionResults 133 E coli and 117 K pneumoniae were isolated where 652 of ESBL were detected With modified CLSI method overall rate of ESBL positivity increased from 652 to 744of E coli and 743 of K pneumoniae isolates were ESBL producers by modified CSLI MethodConclusion All the clinical samples growing gram negative bacteria should be tested for ESBL production Considering the grave scenario of antibiotic resistance in our country it is high time that all clinical laboratories start detecting these enzymes routinely and accuratelyKeywords Escherichia coli Klebsiella pneumoniae ESBL Modified CLSI guidelines
Authors and Affiliations
Sumangala B, Akshantha B Sangannavar, Sahana Shetty N. S
Keywords
Related Articles
- EP ID EP485857
- DOI 10.18231/2581-4761.2018.0026
- Views 85
- Downloads 0
Changing trend in clinico-mycological profile of dermatophytosis of skin in Eastern India
Introduction Dermatophytosis is one of the most prevalent cutaneous mycosis and a public health problem in West Bengal as well as in India Its footprint spans far and wide across urban and rural Bengal with a distributio...
Mycological profile of keratomycosis in a tertiary care centre from Pune Maharashtra
Introduction Microbial keratitis remains a leading cause of corneal ulcer and blindness worldwide Mycotic keratitis has emerged as a major ophthalmic problem and contributes to 653 of all corneal infections worldwide Thu...
Evaluation of BAL versus sputum specimen for the diagnosis of pulmonary tuberculosis in sputum AFB smear negative patients- retrospective study at PIMSR, Gujarat
Aims and Objective Early diagnosis of smear negative tuberculosis is a significant challenge in control of tuberculosis The present retrospective study was done on sputum and BAL samples of the same patients for better d...
Bacterial profile of central line associated blood stream infections in I.C.U patients from tertiary care hospital
Introduction Central line associated bloodstream infection CLABSI is a major contributing factor inhospital mortality and morbidity CLABSI are considered among the first and most quotpreventablequot classes of nosocomial...
Swamp Fever in Horse: A Brief Overview
Swamp fever also known as equine infectious anemia is a viral disease of horses. The etiology belongs to the family Retroviridae and is transmitted by blood sucking insects and mosquitoes. Different strains of the virus...