Phenytoin induced cerebellar atrophy: A case report
Journal Title: Panacea Journal of Medical Sciences - Year 2018, Vol 8, Issue 1
Abstract
The significant doserelated as well as idiosyncratic drug toxicity are encountered in pediatric practice occasionally due to the zero order pharmacokinetics and narrow therapeutic margin of phenytoin Among uncommon side effects reported in patients with phenytoin exposure are cerebellar atrophy and at times its clinical presentation is masquerading as acute encephalitis An unusual presentation of phenytoin toxicity in a 15yearold girl suffering from multiple tubercular with seizure who developed bilateral cerebellar atrophy besides other features of Phenytoin toxicity over 3 years of drug use has been reported here along with possible approaches to minimize the possibility of dosing error in its prescriptionKeywords Phenytoin Cerebellar atrophy Multiple tuberculoma
Authors and Affiliations
Kumari Pratima, Shivlok Narayan, Alka Agarwal
Keywords
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- EP ID EP487051
- DOI 10.18231/2348-7682.2018.0010
- Views 75
- Downloads 0
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