Photoacoustic Imaging: Hybrid Technology for Small Animals Holding Potentials Translatable for Clinical applications
Journal Title: JOURNAL OF ADVANCES IN PHYSICS - Year 0, Vol 4, Issue 1
Abstract
Photoacoustic imaging is an emerging modality that exploits the photoacoustic effect to combine the high contrast of optical imaging with the spatial resolution and penetration depth of ultrasound. A key feature of PA imaging methods is that they exploit optical contrast but employ US detection principles. The PA effect offers a way to take advantage of the ability of light to penetrate into the body and let us defeat light diffusion by using US waves to see the penetrating light. The main advantage of this hybrid approach is that the optical properties of biological tissue, including high contrast and spectral specificity, are encoded in an ultrasound signal. Resolutions of better than 1 mm can be obtained at depths measured in centimeters (up to 7) and not in millimeters, depending on the laser wavelength and transducer frequency used, opening up entirely new regimens of optical imaging. From a clinical standpoint, PA imaging is complementary in nature and synergetic with US and a combined US and PA imaging system can be easily implemented due to the presence of a shared detector and associated electronics. Furthermore, such a system will be readily accepted by clinicians familiar with US imaging.
Authors and Affiliations
Daniela Berritto, Francesca Iacobellis, Maria Paola Belfiore, Michele La Porta, Roberto Grassi
Keywords
Related Articles
- EP ID EP653515
- DOI 10.24297/jap.v4i1.2042
- Views 63
- Downloads 0
The Development of Relativity and Einstein
There are errors in general relativity that must be rectified. As Zhou pointed out, Einsteins covariance principle is proven to be invalid by explicit examples. Linearization is conditionally valid. Pauli's version of th...
Ammonia Gas Sensing Characteristics of Spin Coated Polyaniline Films
The conductive layer of emeraldine base polyaniline (PANI) thin film coated on silicon has successfully tested for ammonia. The bulk PANI powder was synthesized by oxidative polymerization of aniline using ammonium perox...
Rapidity Distribution of Charged Pions From Pb+Pb and Au+Au Central Collisions
Rapidity distributions for charged pions produced from central collisions Pb+Pb and Au+Au at (b ≤ 3.4 fm.) in range of energy 2 GeV up to = 200 GeV are investigated. The experimental results are studied in terms...
MAGNETIC AND ELECTRICAL PROPERTIES OF ELECTRON BEAM GUN DEPOSITED [Mn/Al] MULTILAYERED FILMS
By following electron beam gun evaporation technique, the magnetic multilayers in the configuration, [Mn(60nm)/Al(20nm)]n; n =1, 2 and 9 were deposited at 473K, under high vacuum conditions. From grazing incidence X- r...
Influence of Alloying Additives on The Adhesive Properties of Steels: Atomic Level Simulation
In the present work we report atomistic molecular dynamics simulation results on adhesion force between self-mated iron/iron, iron/vanadium, iron-cementite and iron/titanium surfaces has been determined and we found that...