Phototherapy induced hypocalcemia in neonates: A case–control prospective study

Journal Title: Indian Journal of Child Health - Year 2018, Vol 5, Issue 3

Abstract

Objective: The objective of the study was to evaluate the adverse effects of phototherapy both total and ionic calcium levels in neonates. Methods: A case–control prospective study was conducted in the Department of Pediatrics, over a period of 15 months. All neonates preterm or term with icterus in phototherapy range formed the study group(s). Serum calcium total and ionized were measured on a serial basis. Results: Neonates in the study group had significant fall in total serum calcium after phototherapy (0.94±0.49 mg/dl). Similarly, ionized serum calcium also decreased after phototherapy in study group (0.56±0.36 mg/dl), p<0.001 statistically significant. The overall incidence of hypocalcemia was 9.6%, higher in preterm (11.7%) than term (8.5%) neonates. Jitteriness and irritability both were seen in 25% of the neonates. None of the neonate had convulsion, but it may occur if the level falls further. Conclusions: While giving phototherapy to a premature baby or a sick baby we should monitor serum calcium levels. Prophylactically oral supplementation of calcium may be considered in newborns receiving phototherapy as it induces hypocalcemia.

Authors and Affiliations

Madhu Goyal, Rambabu Sharma, D R Dabi

Keywords

Related Articles

Naphthalene induced hemolysis in a glucose 6 phosphate dehydrogenase deficient neonate - A case report

Glucose-6-phosphate dehydrogenase (G6PD), a critical enzyme in the hexose monophosphate pathway, is a key component in the antioxidant mechanism of all cells, particularly erythrocytes. Its deficiency may manifest in the...

The role of gastric aspirates cytology and micro-erythrocyte sedimentation rate in predicting the early septicemia in newborn babies

Background: Sepsis is an important cause of neonatal morbidity and mortality. The magnitude of problem may be reduced by early detection of amniotic fluid infections and appropriate treatment of the neonate. Objective: T...

Cord blood Vitamin D levels in newborns and its correlation with anthropometric indices of baby: A cross-sectional study

Objectives: The objectives were to study the cord blood Vitamin D levels in term neonates and the association of Vitamin D deficiency with birth weight and crown-heel length. Materials and Methods: This cross-sectional s...

Validity of non-invasive hemoglobin measured by pulse co-oximeter in neonates - An observational study

Background: Hemoglobin is a frequently ordered investigation in neonatal intensive care units. There is a need for hemoglobin estimation by point of care methods to reduce iatrogenic anemia and to alleviate pain associat...

Congenital malaria: Is it really rare? A case report

A 7-day-old term male infant weighing 2.4 kg was admitted with fever, pallor, icterus, and splenomegaly for 3 days. The primi mother was treated for pyrexia in the last trimester. Investigation revealed anemia, hyperbili...

Download PDF file
  • EP ID EP462997
  • DOI -
  • Views 77
  • Downloads 0

How To Cite

Madhu Goyal, Rambabu Sharma, D R Dabi (2018). Phototherapy induced hypocalcemia in neonates: A case–control prospective study. Indian Journal of Child Health, 5(3), 208-212. https://europub.co.uk/articles/-A-462997