Physiological role of myosin light and heavy chain isoforms in fast- and slow-twitch muscles: effect of exercise
Journal Title: Biology of Sport - Year 2009, Vol 26, Issue 3
Abstract
The aims of the present study were to show the distribution of individual myosin light chain (MyLC) isoforms in fast-twitch (FT) and slow-twitch (ST) muscles and between FT muscles in order to find differences between MyLC isoforms in these muscles, to identify similarities with the distribution of myosin heavy chain (MyHC) isoforms and to investigate changes in these relations during adaptation to endurance and resistance training. Male Wistar strain rats were used in this study. One-dimensional electrophoresis was used for separation of MyHC and MyLC isoforms and two-dimensional electrophoresis was used for identification of MyLC different isoforms. A difference in the relative content of MyLC isoforms between FT muscles exists only in the case of MyLC 1slow and 2slow isoforms. Differences in the relative content of MyHC between FT muscles are considerably larger than differences in the MyLC isoforms. MyHC and MyLC isoforms both participate in the remodelling of contractile proteins during exercise training. In conclusion: The present study shows some discrepancy between the modulation of MyHC and MyLC isoforms in muscles with different oxidative potential during adaptation to endurance and resistance training. In ST muscles, there is full agreement between the increase in the relative content of MyHC IIa isoform and MyLC 2fast and 3fast isoforms during resistance training without significant changes during endurance training. The ratio of MyLC 3 and MyLC 2 isoforms increases during both types of exercise training, but it is two times higher during resistance training.
Authors and Affiliations
K Alev, P Kaasik, A Pehme, M Aru, AM Parring, T Seene
Keywords
Related Articles
- EP ID EP58971
- DOI -
- Views 116
- Downloads 0
Evaluation of the knee laxities of wrestlers
Anterior tibial displacements of 78 elite wrestlers (20.7±3.1 years of age), 49 of them wrestling in Greco-Roman and 29 in free style, having no history of serious knee injury were measured by KT1000 (MEDmetric, San Dieg...
ACUTE EFFECTS OF A RESISTED DYNAMIC WARM-UP PROTOCOL ON JUMPING PERFORMANCE
This study aimed to investigate the kinematic and kinetic changes when resistance is applied in horizontal and vertical directions, produced by using different percentages of body weight, caused by jumping movements duri...
Effects of different frequencies of whole body vibration on muscular performance
The effects of different frequencies (20, 30, and 40Hz) of whole body vibration were analyzed in order to determine which one of them is the most effective for muscular performance training. Thirty-one subjects participa...
Sensation seeking in males involved in recreational high risk sports
The study examined sensation seeking intensity level in males involved in recreational high risk sports and investigated whether its level depends on type of sport practised. Additionally, in case of parachutists, sport...
The effect of estrogen on muscle damage biomarkers following prolonged aerobic exercise in eumenorrheic women
This study assessed the influence of estrogen (E[sub]2[/sub]) on muscle damage biomarkers [skeletal muscle - creatine kinase (CK); cardiac muscle - CK-MB] responses to prolonged aerobic exercise. Eumenorrheic women (n=10...