PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITY OF THE METHANOL LEAF EXTRACT OF LUFFA CYLINDRICA ON CERTAIN PATHOGENIC MICROBES.
Journal Title: World Journal of Pharmaceutical Research - Year 2017, Vol 6, Issue 11
Abstract
The attention of the pharmaceutical scientists has been drawn to studies on the potential antimicrobial activities of plant derived substances, an untapped source of antimicrobials which are used in traditional medicine in different settings. This led to the study of the phytochemical analysis and antimicrobial activity of the methanol leaf extract of Luffa cylindrica on certain pathogenic microbes: Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhi, Candida albicans, Aspergillus niger, which were isolated from the laboratory benches and toilet handles of the Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University Awka. The percentage Ash value was determined to be 2.3%. Microscopic evaluation of the plant showed specific cellular structures like the parenchyma, oxalate crystals, epidermal hairs and stomata. S. aureus, S. typhi, P. aeruginosa and C. albicans were susceptible to the methanol leaf extract of L. cylindrica, with the exception of E. coli and A. niger which were resistant to the methanol extract. The phytochemical compounds present are Flavonoids, Alkaloids, Saponins, Anthraquinone, Terpenoids, Steroids. Overall, among the pathogenic microbes used, E. coli and A. niger were resistant to the effect of the leaf extract of Luffa cylindrica.
Authors and Affiliations
Dr. Ezea Charity Chinasa
Keywords
Related Articles
- EP ID EP618212
- DOI -
- Views 121
- Downloads 0
ISOLATION AND IDENTIFICATION OF CONTAMINANT FUNGI OF SOME FOOD SUPPLEMENTS IN MOSUL CITY, IRAQ(*)
Study of isolation and identification of fungi which contaminate some food supplements which available in mosul pharmacies, which were (15) samples, showed that all these samples were contaminated with fungi except orang...
PHYTOCHEMICAL AND ETHNO-PHARMACOLOGICAL PROPERTIES OF LASIA SPINOSA (KOHILA): A REVIEW
In the present review, an attempt has been made to put together the traditional, phytochemical and pharmacological studies done on an important medicinal plant Lasia spinosa. It is a large herbaceous plant that belongs t...
A REVIEW ON TREATMENT OF PATIENT ADHERENCE TOWARDS OBESITY CONTRIBUTES TO THE DEVELOPMENT OF TYPE-II DIABETES MELLITUS
A number of studies show that the risk of developing type-II diabetes is closely linked to the presence and duration of overweight as well as obesity. Indeed, 90% of individuals with type-II diabetes are either overweigh...
SEROPREVALENCE AND RISK FACTORS OF TOXOPLASMA GONDII INFECTION AMONG HEALTHY BLOOD DONORS IN ALRIBAT TEACHING HOSPITAL KHARTOUM STATE, SUDAN
Toxoplasmosis is an opportunistic, zoonotic disease with a worldwide distribution. There are large variations in the seroprevalence of T. gondii infection in different regions of the world. Toxoplasmosis is a common para...
BRIEF REVIEW OF GANDHAKA WITH IT'S KUSTHAGHNA PROPERTY
Gandhaka (sulphur) is the first mineral drug in ‘Uparasa group’.[1] It is a multi-valent non-metal which is abundant. In its native form, sulpher is a yellow crystalline solid, which is odourless and tasteless.In Rasasha...