PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL SCREENING OF METHANOL EXTRACT OF ANNONA MURICATA L. LEAVES
Journal Title: International Journal of Research in AYUSH and Pharmaceutical Sciences - Year 2017, Vol 1, Issue 4
Abstract
The plant Annona muricata (soursop)is used in traditional medicine for the treatment of many disease conditions such as diabetes, dysentery and malaria. Hence, the need for a scientific study to justify some of the curative claims associated with its use by local healers. To achieve this, we carried out cold maceration extraction on the leaves using methanol as extracting solvent. Phytochemical analysis of the crude extract shows that flavonoids, saponins, and tannins were present, while alkaloids and anthraquinones were absent. The extract was tested for anti-microbial activities on both bacterial and fungal isolates using ciprofloxacin and econazole as positive controls respectively. The isolates used in this study were Staphylococcus aureus, Salmonella typhi, Klebsiella pneumoniae, Pseudomonas aeruginosa, Candida albicans and Aspergillus niger. Results show that the extract was active on Staphylococcus aureus, Salmonella typhi, Klebsiella pneumoniae and Pseudomonas aeruginosa but inactive on Candida albicans and Aspergillus niger, an indication that the plant extract possessed only antibacterial, and no antifungal, activities. The zone of growth inhibition ranged from 12 to 20 mm with variable MIC and MBC values. These results support the use of the soursop leaf concoction as herbal medication for the treatment of various bacterial diseases.
Authors and Affiliations
Nuhu A. A
Keywords
Related Articles
- EP ID EP420476
- DOI -
- Views 82
- Downloads 0
AYURVEDIC APPROACH OF DIABETIC FOOT ULCER
Diabetes Mellitus is disease known from the dawn of civilization. Sedentary life style, lack of exercise, faulty dietary habits, improper medication and urbanization precipitate the disease. It is estimated that the tota...
A RANDOMISED SINGLE BLIND ACTIVE CONTROLLED, PARALLEL GROUP STUDY COMPARING THE EFFICACY & SAFETY OF THE KARNIM PLUS® CAPSULES IN PATIENTS WITH MILD OR MODERATE DIABETES MELLITUS TYPE. II
Diabetes is the most prevalent disease in the world affecting middle and old aged persons of the world directly impacting their life style and other metabolic hazards. Karnim plus is a remedy of Unijules Life Sciences lt...
ROLE OF MEDHYA RASAYANA (NOOTROPIC HERBS) IN PRESENT SCENARIO: AN AYURVEDIC OVERVIEW
Rasayanatantra is a branch of Ayurveda which describes the measures of attaining long life, maintenance of youthfulness, increasing immunity and providing excellent nutrition to all the body tissues. Rasayana on regular...
PHARMACOGNOSTICAL STUDIES AND PRELIMINARY PHYTOCHEMICAL INVESTIGATION ON THE BARK OF BAUHINIA VARIEGATA (CAESALPINIACEAEA)
Bauhinia variegata (Family - Caesalpiniaceaea) is a medium-sized, deciduous tree, found throughout India, ascending to an altitude up to 1800m in Himalayas. The objective of the study was to develop various standardizati...
PROSPECTIVE APPROACH ON DIAGNOSIS AND MANAGEMENT OF NIDRAVIKARA (SLEEP DISORDER/ INSOMNIA) IN AYURVEDA
Sleep is an essential component of human life to keep health and well-being absence of which cause a lot of neuro-psycho–physiological derailment in the body. In another words if normal sleep is disturbed for a short tim...