PHYTOCHEMICAL AND ANTI-CONVULSANT STUDY OF NYCTANTHES ARBOR-TRISTIS EXTRACT
Journal Title: International Journal of Pharmacognosy - Year 2018, Vol 5, Issue 5
Abstract
The drug is obtained from the dried fruit of Nyctanthes arbor-tristis of family Oleaceae. It is also called Coral Jasmine, Parijat, and Harsingar etc. To confirm the veracity of aforementioned claim, the anticonvulsant effect of the ethanolic extract has been evaluated. In this investigation, the rats were pretreated with different dose of Nyctanthes arbor-tristis ethanolic extract (100, 200 mg/kg) for 14th days and then, they were subjected to maximal electroshock-seizures, the dose of 100 and 200 mg/kg significantly reduced the duration of hind limb extension and both the doses were statistically found to be equipotent. The reference, standard, Phenytoin (30 mg/kg) provided complete protection. Thus, present study revealed anticonvulsant effect of Nyctanthes arbor-tristis against maximal electroshock-induced convulsion in rat.
Authors and Affiliations
Sweta Pundir
Keywords
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