PHYTOCHEMICAL AND ANTIBACTERIAL POTENTIAL OF ACETONE LEAF EXTRACT OF ACACIA CONCINNA (WILLD.) DC.
Journal Title: International Journal of Pharmacognosy - Year 2016, Vol 3, Issue 3
Abstract
The present study was aimed to find out the antimicrobial potential of acetone extract of Acacia concinna leaf against five different bacterial strains at 100 and 200mg/ml concentrations. The disc diffusion assay was performed to access the antimicrobial potential of the extract. The agar plate containing a bacterial culture was divided into 4 zones and each zone was independently impregnated with four sterile filter paper discs (6mm in diameter) containing (10µl of each concentration) distill water (Negative control), ampicillin (Positive control); Acacia Concinna leaf extract (100mg/ml and 200mg/ml as Test). Zone of inhibition and MIC (minimum inhibitory concentration) for test drug was evaluated to access the antimicrobial potency. The phytochemical analysis shows the presence of alkaloids, tannins and glycosides that might be responsible for the aimed biological activities. Out of five bacterial strains, the test drug exhibit zone of inhibition against Mycobacterium smegmatis and Bacillus subtalis in concentration dependent manner. Minimum inhibitory concentration (MIC) of test drug against Mycobacterium smegmtis and Bacillus subtilis, was found to be 2.5 (mg/ml) and 1.25 (mg/ml) respectively. The basis of above findings suggests the need for further future perspective works on the plant extract of Acacia Concinna which might be very useful as it seems to be a potential source for arresting the growth and metabolic activities of strains like Mycobacterium smegmtis and Bacillus subtilis.
Authors and Affiliations
Pushpa Dahiya et al.
Keywords
Related Articles
- EP ID EP428390
- DOI -
- Views 115
- Downloads 0
HERBS FOR COMBATTING DERMATOPHYTOSIS- A REVIEW
Infinite varieties of plants- both medicinal and aromatic are seen on the Indian continent. Siddha system of medicine is effectively making use of them. Sage Yugi have classified skin diseases into 18 kuttas. Pundareega...
COMPARATIVE PHYSICOCHEMICAL, PHYTOCHEMICAL AND HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY EVALUATION OF STEM BARK AND SMALL BRANCHES OF AILANTHUS EXCELSA ROXB.
Over-harvesting of many traditional medicinal plants has become a threat to the country’s species diversity and has resulted in the endangerment of certain medicinal plant species. In the near future, many plant species...
STUDY OF ANTIOXIDANT POTENTIALS OF ALKALIPHILIC CYANOBACTERIA ISOLATED FROM LONAR LAKE, INDIA
Seven different cyanobacterial species belonging to 4 genera were isolated from the alkaline Lake Lonar, situated in the Buldhana district of Maharashtra. The phycocyanin producing ability of all the isolates was screene...
INVESTIGATION ON NOVEL ROLE OF SOLANUM XANTHOCARPUM AND JUNIPERUS COMMUNIS EXTRACT AGAINST CCl4 INDUCED LIVER INJURY
Background: There are very less therapeutic and reliable liver protective drugs in modern medicine to prevent and treat liver injury caused due to drugs. Traditionally Solanum xanthocarpum Schradt. (SX) and Wendl. and Ju...
ANTIMICROBIAL ACTIVITY OF METHANOLIC EXTRACT OFCISSUS PALLIDA
Herbs have been widely used for centuries as remedies for diseased human conditions as they have certain phytochemicals of diseases curing nature. The present study explains the antimicrobial (antibacterial & antifungal)...