Phytochemical and Pharmacological Investigation of Hyptis suaveolens L. in Experimental Models
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2017, Vol 6, Issue 1
Abstract
Hyptis suaveolens L. Poit is a plant belonging to family Lamiaceae, or the Mint family..The original family name is Labiatae, while this is still considered a suitable alternate name nearly all botanists now use the name "Lamiaceae" in referring to this family. It is also called Ballota suaveolens Linn, (Kirtikar and Basu, 1999). The word diabetes is Greek for a draw off, referring to the ejection of a more quantity of urine; and mellitus is Latin used for sugar. Consequently diabetes mellitus means the passage of huge amounts of sweet urine. The plant materials (1 kg) were initially defatted with petroleum ether and then extracted with alcohol and water using a Soxhlet apparatus. The yield of the plant extracts ethanol (95%) and aqueous measured about 20 g each after evaporating the solvent using water bath. The standard extracts obtained from Hyptis suaveolens L. Were then stored in a refrigerator at 4°C for further use for phytochemical investigation and pharmacological screening. Diabetes was induced by intra-peritoneal injection of Alloxan monohydrate (150 mg/kg b.w.) dissolved in the in normal saline (Viana et al, 2004). Blood was withdrawn (0.1 ml) from the tip of the tail of each rat under mild ether anesthesia. Animals were considered diabetic when the blood glucose level was raised beyond 200 mg/100 ml of blood. This condition was observed at the end of 72 h after alloxanisation.
Authors and Affiliations
Dharmendra Singh*| Research Scholar, OPJS, University, Churu, Rajasthan, India, Anil Kumar Middha| Associate Professor, OPJS, University, Churu, Rajasthan, India
Keywords
Related Articles
- EP ID EP3817
- DOI -
- Views 383
- Downloads 24
H1N1 AND MOLECULAR DIAGNOSIS- RAPID AND EASE IN VIRAL AND DISEASE MONITORING
Influenza a viruses are medically significant pathogens responsible for higher mortality and morbidity throughoutthe world. Swine influenza known to be caused by influenza A subtypes H1N1, H1N2, H2N3,H3N1, and H3N2, is a...
RP-UFLC-DAD METHOD FOR THE DETERMINATION OF PIPERACILLIN AND TAZOBACTAM SODIUM IN BULK AND MARKETED FORMULATIONS
Aim: To develop a simple, sensitive, rapid, robust and reproducible method for the simultaneous determination of piperacillin and tazobactam sodium using ultra fast chromatographic method (UFLC). Materials and Methods: T...
INVITRO ANTIOXIDANT ACTIVITY AND HPTLC ANALYSIS OF WITHANIA SOMNIFERA
Withania somnifera is a well known medicinal plant having wide range of medicinal properties. HAEWS, MEWS and AEWS were comparatively standardized for the content of Withanolide D by HPTLC. All the samples were screened...
PREPARATION AND EVALUATION OF IMIQUIMOD LOADED SOLID LIPID NANOPARTICLES BASED TOPICAL GEL FORMULATION: PART-I
Solid lipid nanoparticles are at the forefront of the rapidly developing field of nanotechnology with several potential applications in drug delivery, clinical medicine and research as well as in other varied sciences....
SEROFREQUENCY OF HEPATITIS D VIRUS AMONG HEPATITIS B INFECTED PATIENTS, KHARTOUM STATE, SUDAN.
Background: Hepatitis Delta virus (HDV) is a defective RNA virus dependent on Hepatitis B virus (HBV) infection for its replication and expression. It is estimated that approximately 5% of hepatitis B surface antigen (Hb...