PHYTOCHEMICAL EVALUATION AND PHARMACOLOGICAL ACTIVITY OF SYZYGIUM AROMATICUM: A COMPREHENSIVE REVIEW
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2014, Vol 6, Issue 8
Abstract
Medicinal plants are generating an ever-increasing amount of interest due to the effectiveness, low cost and minimal side-effects associated with drugs derived from them. Clove (Syzygium aromaticum (L.) (Family Myrtaceae) is one of the most important herbs in traditional medicine, having a wide spectrum of biological activity. Phytoconstituents of clove comprise of various classes and groups of chemical compounds such as monoterpenes, sesquiterpenes, phenolics and hydrocarbon compounds. The major phytochemicals found in clove oil is mainly eugenol (70-85%) followed by eugenyl acetate (15%) and β-caryophyllene (5–12%). Their derivatives result in biological benefits such as antibacterial, antifungal, insecticidal, antioxidant, anticarcinogenic capacities. In addition to clove oil’s worldwide use as a food flavoring agent, it has also been employed for centuries as a topical analgesic in dentistry. This review presents an overview and details of the phytochemical and pharmacological investigations on the S. aromaticum.Â
Authors and Affiliations
Monika Mittal, Nomita Gupta, Palak Parashar, Varsha Mehra, Manisha Khatri
ENHANCEMENT OF DISSOLUTION RATE OF HYDROCHLOROTHIAZIDE
Objective: The aim of this study was to enhance the dissolution rate of hydrochlorothiazide (HCTZ).Methods: Binary solid dispersions (SDs) of HCTZ with increasing weight ratios of poloxamer 407, polyethylene glycol 6000...
DESIGN AND EVALUATION OF MODIFIED CHITOSAN BASED IN SITU GEL FOR OCULAR DRUG DELIVERY
Objective: The object of the present study was to formulate and evaluate in-situ gel of modified chitosan by using temperature triggered method to improve bioavailability.Methods: Modified chitosan-based moxifloxacin HCl...
INDUCTION OF CASPASE-3 DEPENDENT APOPTOSIS, CELL CYCLE ARREST AND CYTOTOXICITY IN BREAST CANCER CELLS BY ABRUS PRECATORIUS
Objective: To evaluate the leaf extract of Abrus precatorius as a potential therapy for breast cancer treatment.Methods: Aqueous leaf extracts of A. precatorius was prepared by the process of maceration. The collected fi...
EFFECT OF ETHANOL-WATER COMPOSITION ON CLINDAMYCIN HYDROCHLORIDE PSEUDOPOLYMORPHISM
Objective: Formation of clindamycin hydrochloride (clindamycin HCl) in monohydrate-ethanolate from the recrystallization process with ethanol–water (5:2) has been reported a long time ago. However, the effect of ethano...
1,3,4-THIADIAZOLE: A BIOLOGICALLY ACTIVE SCAFFOLD
There has been considerable interest in the development of novel compounds with anticonvulsant, antidepressant, analgesic, anti-inflammatory, anti allergic, antipsychotic, antimicrobial, antimycobecterial, antitumour, an...