PHYTOCHEMICAL EVALUATION AND PHARMACOLOGICAL ACTIVITY OF SYZYGIUM AROMATICUM: A COMPREHENSIVE REVIEW

Abstract

Medicinal plants are generating an ever-increasing amount of interest due to the effectiveness, low cost and minimal side-effects associated with drugs derived from them. Clove (Syzygium aromaticum (L.) (Family Myrtaceae) is one of the most important herbs in traditional medicine, having a wide spectrum of biological activity. Phytoconstituents of clove comprise of various classes and groups of chemical compounds such as monoterpenes, sesquiterpenes, phenolics and hydrocarbon compounds. The major phytochemicals found in clove oil is mainly eugenol (70-85%) followed by eugenyl acetate (15%) and β-caryophyllene (5–12%). Their derivatives result in biological benefits such as antibacterial, antifungal, insecticidal, antioxidant, anticarcinogenic capacities. In addition to clove oil’s worldwide use as a food flavoring agent, it has also been employed for centuries as a topical analgesic in dentistry. This review presents an overview and details of the phytochemical and pharmacological investigations on the S. aromaticum. 

Authors and Affiliations

Monika Mittal, Nomita Gupta, Palak Parashar, Varsha Mehra, Manisha Khatri

Keywords

Related Articles

DESIGN ZOLMITRIPTAN LIQUISOLID ORODISPERSIBLE TABLETS AND THEIR IN VITRO EVALUATION

Objective: The objective of present study is to develop orodispersible tablets (ODTs) of zolmitriptan by liquisolid technique using different types of super disintegrants to enhance the disintegration and dissolution of...

EVALUATION OF CYTOTOXIC AND GENOTOXIC EFFECTS OF ZERUMBONE ON COLON ADENOCARCINOMA COLO205 CELLS AND HUMAN LYMPHOCYTES

Objective: The objective of the present study was to investigate the growth inhibitory effect, apoptosis initiation and genotoxic effect of zerumbone (ZER), a phytochemical and cisplatin, a chemotherapeutic drug on human...

EFFICACY OF UNANI FORMULATIONS IN CHRONIC ENDOCERVICITIS: A RANDOMIZED COMPARATIVE STUDY

Objective: To compare the efficacy of Unani formulation in chronic endocervicitis.Methods: A parallel, comparative randomized trial was conducted at Govt. Nizamia General Hospital, Hyderabad from 1998 to 2000 in 50 patie...

AROMATASE INHIBITORS - TYPES AND ADVANTAGES

The role of aromatase inhibitors in the management of breast cancer has been promising as it markedly suppresses the production of estrogen. The inhibitors are very effective in postmenopausal women and used as the first...

RAPID AND VALIDATED HPLC-UV METHOD FOR DETERMINATION OF GEMIFLOXACIN IN HUMAN URINE

Objective: To develop and validate a simple and rapid reversed phase high performance liquid chromatographic (RP-HPLC) method for the determination of Gemifloxacin (GFX) in human urine.Methods: GFX was isolated from urin...

Download PDF file
  • EP ID EP579662
  • DOI -
  • Views 87
  • Downloads 0

How To Cite

Monika Mittal, Nomita Gupta, Palak Parashar, Varsha Mehra, Manisha Khatri (2014). PHYTOCHEMICAL EVALUATION AND PHARMACOLOGICAL ACTIVITY OF SYZYGIUM AROMATICUM: A COMPREHENSIVE REVIEW. International Journal of Pharmacy and Pharmaceutical Sciences, 6(8), 67-72. https://europub.co.uk/articles/-A-579662