PHYTOCHEMICAL PROFILING OF SUCCESSIVE EXTRACTS OF FRUIT AND STEM BARK OF SOLANUM PUBESCENS
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2014, Vol 6, Issue 9
Abstract
Objective: Solanum (L) is the most representative genus of Solanaceae, Solanum species are a rich source of bioactive compounds which are known to possess a variety of biological activities. Solanum pubescens is a wild plant growing abundantly as weed in forest and the hills of South-Eastern Ghats in Andhra Pradesh. This study purposed to investigate the phytochemical constituents present in different extracts of Solanum pubescens.Methods: Solvents such as hexane, chloroform, ethyl acetate and ethanol, were used to isolate the bioactive compounds from fruit and stem bark. Fluorescence analyses of the plant powder and of different successive extracts were carried out under normal light and UV light.Results: The preliminary phytochemical screening of fruit and stem bark has revealed that oils & fats, alkaloids, flavonoids, carbohydrates, saponins, coumarins and phenolics are present in different extracts. Interestingly, alkaloids are present only in the ethanol extract. The quantitative analysis revealed that Solanum pubescens is very rich in phenolics followed by flavonoids, alkaloids, saponins, carbohydrates and oils, which gives a very strong reason to select this plant for future evaluation for its pharmacological properties. It is interesting to note that this is the first report showing a thorough qualitative and quantitative analysis of fruit and stem bark of Solanum pubescens.Conclusion: This study certainly helps us to detect specifically the cytotoxic compounds, which are presumed to play an important role in exerting curative properties of various ailments.Â
Authors and Affiliations
Haseeb Ur Rahman, Riaz Mahmood, Mir Haris, Nazneen Rahman
Keywords
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