PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL ACTIVITY FROM NERIUM OLEANDER AND EVALUVATE THEIR PLANT MEDIATED NANOPARTICLE SYNTHESIS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 5
Abstract
Phytochemical and antibacterial activity of essential oils obtained from Nerium oleander leaf with the help of three different extracts like ethanol, Methanol, and acetone. In this aqueous leaf extracts confirms the presence of various phytochemicals. To evaluate the antibacterial activities of these aqueous extracts were determined by disc diffusion method. From these three extracts methanol shows strong antibacterial effect on Klebsiella, Pseudomonas, Alkaligenes except Acinetobacter. None of the leaf extracts show no more activity in Acinetobacter. Biologically synthesized nanoparticles have been widely used in the field of medicine. Shade dried leaves of Nerium oleander was used for the synthesis of silver nanoparticles. UV- Visible spectroscopy studies were carried out to assess the formation of Ag nanoparticles. Scanning electron microscope (SEM) was used to characterize the Ag nanoparticle. To compare the antimicrobial activity of silver nanoparticles with the different leaf extracts.
Authors and Affiliations
Suganya R. S. , K. Priya , Sumi Roxy
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