PHYTOCHEMICAL SCREENING AND ANTIDIABETIC ACTIVITY OF DIFFERENT LEAF EXTRACTS FROM LOTUS (NELUMBO NUCIFERA GAERTN.) IN STREPTOZOTOCIN INDUCED MICE

Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2017, Vol 10, Issue 12

Abstract

  Objective: The present study is to evaluate the antidiabetic activity of various extract of Lotus (Nelumbo nucifera Gaertn.) leaf using hexane, ethyl acetate, and ethanol organic solvent.Methods: Standard phytochemical screening method and streptozotocin induced diabetic mice.Result: The phytochemical screening showed only ethyl acetate of lotus leaf extract contains the flavonoids. The ethyl acetate lotus leaf extract (dose level 150 mg/kg) showed a significant reduction of the blood glucose.Conclusion: The ethyl acetate extract of lotus leaf (N. nucifera Gaertn.) had the hypoglycemic effect on diabetic induced mice.

Authors and Affiliations

Ruth Mayana Rumanti, Marline Nainggolan, Urip Harahap

Keywords

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  • EP ID EP605526
  • DOI 10.22159/ajpcr.2017.v10i12.20888
  • Views 88
  • Downloads 0

How To Cite

Ruth Mayana Rumanti, Marline Nainggolan, Urip Harahap (2017). PHYTOCHEMICAL SCREENING AND ANTIDIABETIC ACTIVITY OF DIFFERENT LEAF EXTRACTS FROM LOTUS (NELUMBO NUCIFERA GAERTN.) IN STREPTOZOTOCIN INDUCED MICE. Asian Journal of Pharamceutical and Clinical Research, 10(12), 190-192. https://europub.co.uk/articles/-A-605526