PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY OF ECLIPTA ALBA L.
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2019, Vol 12, Issue 2
Abstract
Objective: Earlier various studies on pharmacological and therapeutic properties of Eclipta alba L. have been reported. The present investigation is on phytochemical screening and antioxidant activity of E. alba L. using different solvent extracts. Method: The shade-dried and grounded E. alba L. plant materials were treated with petroleum ether, chloroform, ethyl acetate, ethanol, methanol, and water (aqueous) solvents. The extracted residue was then dissolved in dimethylsulfoxide and further used for phytochemical screening and antioxidant studies. Results: E. alba L. on different solvent extract, the extractive yield was higher in methanol (14.22±0.99% w/w). The phytochemical screening analysis showed high number of secondary metabolites in the aqueous extract compared to other solvent studied. The metabolite flavonoids, phenols, and tannins are likely to be antioxidant potential compound. Hence, further, the total flavonoid content determination showed high of 0.875±0.020 μg/g in methanol extract. Further antioxidant property of E. alba L. was studied by method such as1,1-diphenyl-2-picrylhydrazyl radical scavenging activity, nitric oxide scavenging activity, metal chelating activity, and superoxide dismutase activity which showed high antioxidant potency with IC50 values of 62.76±0.63 μg/ml, 96.24±0.34 μg/ml, 72.29±0.61 μg/ml, and 108.40±0.52 μg/ml, respectively, in the petroleum ether extract. Conclusion: From the present study, the substantiate result of antioxidant studies has been obtained from petroleum ether extract . Furthermore the extractive value and flavonoid content was observed to be high in methanol extract. The antioxidant potency of E. alba L. was found to be high in petroleum ether extract compared to other solvent studied.
Authors and Affiliations
Thenmozhi M, JAYANTHI M
Keywords
Related Articles
- EP ID EP608765
- DOI -
- Views 132
- Downloads 0
BIOLOGICAL ACTIVITY AND MOLECULAR DOCKING OF 2’-BROMO-4-METHOXY-3-NITRO BENZIL, 2,2’-DIBROMO BENZIL, AND 4,4’-DICHLORO BENZIL
Objective: A series of benzil compounds have been synthesized by oxidation of corresponding benzoins which in turn were prepared from respective aldehydes. Using this protocol, three new benzils were prepared in good-to-...
COMPARISON OF HERBAL MOUTHWASH WITH COMMERCIALLY AVAILABLE 0.2% CHLORHEXIDINE AND 2% BETADINE MOUTHWASHES IN PATIENTS AFTER STAGE-1 IMPLANT SURGERY
  Objective: The objective of the current study is to assess the antibacterial efficiency of an herbal mouthwash (clove and neem) against 0.2% chlorhexidine and 2% betadone mouthwash in patients who have undergone Stag...
CONVENTIONAL AND RECENT DIAGNOSTIC AIDS IN TUBERCULOUS LYMPHADENITIS: A BRIEF OVERVIEW
One of the most common form of extra-pulmonary tuberculosis is peripheral tuberculous lymphadenitis and accounts for 20-40% of the cases. Tuberculous lymphadenitis has a gender and age predilection (usually seen in young...
A CORRELATION BETWEEN THYROID STIMULATING HORMONE AND BODY MASS INDEX IN WOMEN WITH SUBCLINICAL HYPOTHYROIDISM IN NCR
ABSTRACTObjective: Weight gain is a characteristic feature of hypothyroidism. People with subclinical hypothyroidism (SCH) are also characterized by the sameis still unclear.Methods: Height and weight were calculated of...
Professor TOTAL PHENOLIC CONTENT AND FREE RADICAL SCAVENGING ACTIVITY OF MIMUSOPS ELENGI L. LEAVES
Objective: The motive of the current study was to find out the total phenolic content (TPC) and free radical scavenging (FRS) activity of various solvent extracts of leaves. Methods: Leaves powder was subjected to extra...