Phytochemical Screening and Toxicity Studies on the Leaves of Capparis sepiaria Linn. (Capparidaceae)
Journal Title: Journal of Basic and Clinical Pharmacy - Year 2010, Vol 1, Issue 1
Abstract
Capparis sepiaria Linn. (Family: Capparidaceae) is a rare indigenous in South India but has widespread distribution in many tropical and sub-tropical countries. The present study intended with various phytochemical screening and toxicity studies were carried out on the leaves of the Capparis sepiaria. Preliminary phytochemical evaluation of the ethanolic extract of revealed that the presence of reducing sugar, flavonoids, steroids, tannins, glycosides, alkaloids, gums, resins, amino acids, proteins and anthraquinones. The toxicity studies were performed as acute, sub-acute and chronic toxicity determined the LD50 value of 300-5000 mg/kg body weight 4-6 weeks. The results of the various phytochemical tests indicated that the plant to be rich in various biologically active compounds which could serve as potential source of the crude drugs and in addition the plant is not toxic to the experimental model.
Authors and Affiliations
P. Rajesh, V. Kannan, S. Latha
Keywords
Related Articles
- EP ID EP86454
- DOI -
- Views 182
- Downloads 0
Preparation and evaluation of sustained release loxoprofen loaded microspheres
The aim of present study was to formulate and evaluate the loxoprofen loaded Sustained release microspheres by emulsion solvent evaporation technique. Ethylcellulose, a biocompatible polymer is used as the retardant mate...
Phytochemical analysis and hepatoprotective properties of Tinospora cordifolia against carbon tetrachloride-induced hepatic damage in rats
The present study was conducted to evaluate the hepatoprotective activity of different extracts of Tinospora cordifolia against carbon tetrachloride (CCl4) induced liver damage in rats. The pet ether, ethanol and aqueous...
Comparative analysis of antioxidant and phenolic content of chloroform extract/fraction of Terminalia chebula
In the present study, two chloroform extracts of fruits of Terminalia chebula viz.“CHL1” and “CHL 2” prepared by maceration and sequential method respectively was compared for their antioxidant efficacy and phenolic cont...
Antibacterial and Cytotoxic Activity of Ethanol Extract of Mikania Cordata (Burm.F.) B.L. Robinson Leaves
The purpose of the present study to examine the antibacterial and cytotoxic properties of ethanol extract of leaves of Mikania cordata (Burm.f.) B.L. Robinson. To determine antibacterial activities, the extract was teste...
Role of liquid membrane phenomenon in the anti-bacterial activity of Cefuroxime Sodium
The role of liquid membrane phenomenon has been studied in the anti bacterial activity of cephalosporins i.e. Cefuroxime sodium. In our earlier publication [1] it was reported that hydraulic permeability data obtained to...