Phytochemical Screening and Toxicity Studies on the Leaves of Capparis sepiaria Linn. (Capparidaceae)

Journal Title: Journal of Basic and Clinical Pharmacy - Year 2010, Vol 1, Issue 1

Abstract

Capparis sepiaria Linn. (Family: Capparidaceae) is a rare indigenous in South India but has widespread distribution in many tropical and sub-tropical countries. The present study intended with various phytochemical screening and toxicity studies were carried out on the leaves of the Capparis sepiaria. Preliminary phytochemical evaluation of the ethanolic extract of revealed that the presence of reducing sugar, flavonoids, steroids, tannins, glycosides, alkaloids, gums, resins, amino acids, proteins and anthraquinones. The toxicity studies were performed as acute, sub-acute and chronic toxicity determined the LD50 value of 300-5000 mg/kg body weight 4-6 weeks. The results of the various phytochemical tests indicated that the plant to be rich in various biologically active compounds which could serve as potential source of the crude drugs and in addition the plant is not toxic to the experimental model.

Authors and Affiliations

P. Rajesh, V. Kannan, S. Latha

Keywords

Related Articles

FORMULATION AND EVALUATION OF ENTERIC COATED TABLETS OF PROTON PUMP INHIBITOR

The present study was an attempt to formulate and evaluate enteric coated tablets for esomeprazole magnesium trihydrate. Different core tablets were prepared and formulation (F-1) was selected for further enteric coating...

EFFECT OF EXTRACTS OF MURRAYA KOENIGII SPRENG.AND MORUS ALBA LINN. ON THE AGE OF ATTAINMENT OF PUBERTY AND OVARIAN FOLLICULOGENESIS IN RATS

An experiment was conducted to evaluate the effects of methanolic extracts of Murraya koenigii Spreng. (Curry leaf) and Morus alba Linn. (Mulberry leaf) on the age of attainment of puberty, relative ovary and uterus weig...

Antioxidant, Antihyperlipidaemic and Antidiabetic Activity of Eugenia Floccosa Bedd Leaves in Alloxan Induced Diabetic Rats

The ethanol extract of Eugenia floccosa Bedd (Family: Myrtaceae) leaf was investigated for its antioxidant, antihyperlipidaemic and antidiabetic effect in Wistar Albino rats. Diabetes was induced in Albino rats by admini...

ANTIHEPATOTOXIC EFFECT OF MARRUBIUM VULGARE AND WITHANIA SOMNIFERA EXTRACTS ON CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY IN RATS

Marrubium vulgare and Withania somnifera are used in folk medicine of several countries. Many researches showed that they are used for the treatment of variety of diseases due to their antioxidant effects. The present ai...

Therapeutic Drug Monitoring By Reverse Iontophoresis

Therapeutic molecules possessing distinct pharmacokinetic variation, narrow therapeutic index and concentration dependent therapeutic/adverse effects demand constant monitoring. The current methods for blood sampling are...

Download PDF file
  • EP ID EP86454
  • DOI -
  • Views 147
  • Downloads 0

How To Cite

P. Rajesh, V. Kannan, S. Latha (2010). Phytochemical Screening and Toxicity Studies on the Leaves of Capparis sepiaria Linn. (Capparidaceae). Journal of Basic and Clinical Pharmacy, 1(1), 41-46. https://europub.co.uk/articles/-A-86454