Phytochemical Study of Nothapodytes foetida by LC-ESI-MS
Journal Title: JOURNAL OF CHEMISTRY, ENVIRONMENTAL SCIENCES AND APPLICATIONS - Year 2015, Vol 2, Issue 1
Abstract
In the present study, hyphenated technique using dyad system of high performance liquid chromatography with diode array detection directly coupled with electrospray ionization mass spectrometry (LC-ESI-MS) has been employed for identification of camptothecines and some minor constituents of methanol extract from different parts of Nothapodytes foetida on the basis of systematic mass spectrum analysis without isolation and purification of these components. Also, a simple, precise, sensitive and reproducible LC-MS method has been developed for quantification of camptothecin (CPT), a potent cytotoxic isoquinoline alkaloid, in methanol extract from these different parts of Nothapodytes foetida using the same technique.
Authors and Affiliations
E Sharma , B S Arora
Keywords
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- EP ID EP596603
- DOI 10.15415/jce.2015.21001
- Views 177
- Downloads 0
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Phytochemical Study of Nothapodytes foetida by LC-ESI-MS
In the present study, hyphenated technique using dyad system of high performance liquid chromatography with diode array detection directly coupled with electrospray ionization mass spectrometry (LC-ESI-MS) has been emplo...