PHYTOSOME: MOST SIGNIFICANT TOOL FOR HERBAL DRUG DELIVERY TO ENHANCE THE THERAPEUTIC BENEFITS OF PHYTOCONSTITUENTS
Journal Title: Journal of Drug Delivery and Therapeutics - Year 2018, Vol 8, Issue 1
Abstract
Traditional medicinal system relies on the knowledge and clinical expertization of physicians to regulate the indigenous medicinal system for the sake of well being to humans. Considering the bioavailability issues of phytoconstituents, in this review, we have focused on the various aspects of phytosomes in drug delivery. Phytosome technology is used to enhance the absorption of poorly absorbed lipid soluble active constituents from the herb extracts. So, the article covers a brief introduction of phytosomes, their method of development along with its formulation and evaluation parameters such FTIR, NMR etc. Different types of dosages forms are described in the review, merits and demerits are also discussed along with diagrammatic representation of phytosome development technique. So, the article is the direction for future research to increase the absorption of phytoconstituents. Keywords: Bioavailability, FTIR, lipid, NMR, niosomes, phytoconstituents
HPTLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF CINNAMALDEHYDE IN POLYHERBAL FORMULATION WITH ANTI-DIABETIC PROPERTY
In this research article HPTLC method for the estimation of cinnamaldehyde content in cinnamomum zeylanicum, laboratory batches (MC-I, MC-II, MC-III) and marketed formulation (MCM) was developed. In this method, precoate...
Mini Review: Role of Inhibitors in Cancer Therapy
The report presented details on different types of inhibitors and their localized actions on cells. The review presented details from specific studies conducted in cancer clinical care. The work also presented reviews on...
FACTORS AFFECTING PHYSICIAN’S ADHERENCE TO GENERIC DRUG PRESCRIBING PRACTICE IN PRIVATE HEALTH FACILITIES, MEKELLE CITY, NORTHEASTERN ETHIOPIA
Introduction: Generic medicines are produced by multiple manufacturers hence, are usually cheaper than innovator brands and therefore save costs on medicines. Many physicians oppose brand substitution, believing generic...
THE PREVALENCE OF INDIAN COMMON KRAIT ENVENOMATION AND ITS CLINICAL COMPLICATIONS AMONG THE RURAL POPULATIONS OF INDIA
Snake envenomations have been a serious yet often overlooked public health threat especially in tropical and subtropical countries, including Southeast Asia. The medically important venomous land snakes in Southeast Asia...
COMPARISON OF NECK ISOMETRICS VS A COMBINATION OF NECK ISOMETRICS AND SHOULDER ISOMETRICS IN RELIEVING NECK PAIN AND IMPROVING STRENGTH
Introduction: Neck disorders remain a common problem in modern world. Patients with chronic neck pain uses health care services twice as much as the population on average. The origin of neck pain can be multifactorial. A...