PILL BURDEN, DRUG CLASS DISTRIBUTION AND FINANCIAL BURDEN FOR BUYING MEDICINES IN DIFFERENT MODALITIES OF CHRONIC KIDNEY DISEASE PATIENTS: CROSS-SECTIONAL STUDY
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2018, Vol 10, Issue 6
Abstract
Objective: The objective of the study was to assess the pill burden (PB), drug class distribution and financial burden for buying medicines in different treatment modalities of chronic kidney disease (CKD) patients. Methods: A prospective, cross-sectional study was performed in 244 CKD patients and they were divided into 4 groups as follows: pre-dialysis patients (stages 1-5) as group 1, hemodialysis (HD) patients as group 2, peritoneal dialysis (PD) patients as group 3 and renal transplant recipient (RTR) patients as group 4. Data was collected in pre-designed form through direct patient interaction.Results: Out of 244 CKD patients, PB considering the total number of pills/d in different modalities is 12±5 in pre-dialysis, 10±3 in HD, 13±5 in PD, 14±7 in RTR and for the number of drug classes/d in different modalities is 7±3 in pre-dialysis, 7±2 in HD, 8±3 in PD and 9±3 in RTR. On average mean PB in a number of pills/d is 12±5 and number of drug classes/d is 8±3. Among all the patients, the RTR individuals are having high medicinal expenditure in comparison to the other modalities.Conclusion: PB for the number of pills/d is highest in RTR and almost similar in different modalities. Great improvement in reducing the PB as well as financial burden directly or indirectly improves the patient compliance as well as the quality of life.
Authors and Affiliations
Pavithra Cirevalli, Harini Devi Nimmanapalli, Lalith Kumar Parlapalli, Lakshmi Sowjanya Nuthalapati, Anitha Kuttiappan, Siva Kumar Vishnu Bhotla
Keywords
Related Articles
- EP ID EP567488
- DOI 10.22159/ijpps.2018v10i6.26186
- Views 44
- Downloads 0
GENOTOXIC AND MUTAGENIC STUDIES OF THE ANTIEPILEPTIC DRUG LEVETIRACETAM IN PREGNANT RATS AND THEIR FETUSES
Objective: Levetiracetam (LEV) is an anti-epileptic drug, initially approved as an adjunct therapy in adult patients with partial-onset seizures, and used as monotherapy treatment during pregnancy. However, very few, if...
‘BRCA1’ RESPONSIVENESS TOWARDS BREAST CANCER-A POPULATION-WISE PHARMACOGENOMIC ANALYSIS
Objective: In the present pharmacogenomic work, the genetic, epigenetic and environmental factors associated with BRCA1 induced breast cancer, cancer proneness and its variants across different populations like Indian, N...
FREE RADICAL SCAVENGING AND ANTIOXIDANT PROPERTIES OF MARINE RED ALGAE HYPNEA MUSCIFORMIS
Objective: The study focused on determining the antioxidant properties of the Hypnea musciformis methanol crude extracts, from the red algae.Methods: The evaluation of antioxidant properties was determined by 1,1-dipheny...
STUDIES ON ANTIOXIDANT ACTIVITIES OF SIX CULTIVARS OF PIPER BETLE LINN
Objective: To study the existence of difference or similarity on total phenolic content, flavonoid content and antioxidant properties among different cultivars of Piper betle L.Methods: The methanolic extracts of six dif...
EVALUATION OF INVITRO ANTIOXIDANT POTENTIAL OF THE TOTAL CRUDE ALKALOID EXTRACT OF GLYCOSMIS PENTAPHYLLA (RETZ.) CORREA LEAVES
Objective: The present investigation was undertaken to appraise the antioxidant properties and the total crude alkaloid extract of Glycosmis pentaphylla leaves.Methods: Radical attenuating abilities of total crude alkalo...