Piperazine and Pyrazine containing molecules and their diverse pharmacological activities
Journal Title: International Journal of Advances in Scientific Research - Year 2015, Vol 1, Issue 1
Abstract
Efforts were made to synthesize different heterocyclic compounds and their derivatives and were found to posses promising pharmacological compounds. Although piperazine and pyrazine moiety is six membered heterocyclic compounds but is fascinated by scientists because of the diverse biological activities by not only piperazine and pyrazine but its various substituted derivatives as well and having diverse pharmacological activities such antitumor, anticonvulsant, antidepressant, analgesic, antimicrobial, anti?tubercular and anti diabetic, antihistamine, antiinflamatory and other activities. Some compounds also use as flavoring agent in foods. This review is focused on the piperazine and pyrazine derivatives due to its wider applications. They may replace many existing heterocyclic based pharmaceutical compounds. Many drug that containing piperazine and pyrazine moiety while several compounds are in clinical trials.
Authors and Affiliations
Mohammad Asif
Keywords
Related Articles
- EP ID EP326891
- DOI 10.7439/ijasr.v1i1.1766
- Views 189
- Downloads 0
Bluetooth SIG oversees development of the specification and prediction of program that protects Bluetooth pin
Bluetooth implements confidentiality, authentication and key derivation with custom algorithms based on the SAFER+ block cipher. Bluetooth key generation is generally based on a Bluetooth PIN, which must be entered into...
Bioreduction of silver nanoparticles characterizations and their antimicrobial activity
In this investigation we report the bioreduction of silver nitrate to silver nanoparticles using the leaves aqueous extract of Alangium lamarckii. The silver nanoparticles were characterized by UV–vis spectrophotometer,...
Quantitative Method to Assess Acute Stress Related Behavior in Dogs by Using Motion Capture Technology
Animal therapy is a form of healthcare intervention conducted with the aid of therapy animals, most commonly dogs. For a therapy dog to play an active role in animal therapy, an animal therapist must design a therapy pro...
Presacral Hemangiopericytoma: Case Report
Hemangiopericytoma is rare tumor originating from the pericytes, the contractile cells that surround capillaries. This tumor arises from pericapillary cells or pericytes of Zimmerman and can occur anywhere where capillar...
Assessment of multi-metal resistant bacteria from Periyar river, Southern India
A total of thirty bacterial strains were isolated from the water and sediment samples of Periyar River during premonsoon 2015 for multi-metal resistant study. In this study, the bacterial isolates were challenged against...