Pitfalls in the Genetic Identification of Human Remains
Journal Title: Peer Reviewed Journal of Forensic & Genetic Sciences - Year 2018, Vol 1, Issue 2
Abstract
DNA technology is an irreplaceable tool for the identification of human remains, but the reliability of the ante mortem reference data remains a serious concern. We present here two cases where misleading conclusions could be achieved by using only the genetic profile of the missing person's father such as reference sample. Nevertheless, when appropriate reference DNA samples (e.g., the maternal samples) became available, certain identifications were achieved as shown by the probability of maternity (> 99.999%). Thus, all these data together show that extra-pair paternity was found by the way, in both cases. Precautions to avoid misleading conclusions are addressed. From the beginning of PCR era it rose that DNA profiling of human remains could be an irreplaceable tool for personal identification. Now, after two decades, DNA technology represents the golden standard for human identification, which is being used even for mass disaster and mass graves victims. DNA testing is, by definition, a sample-to-sample comparison, and its reliability in the identification of human remains depends from several factors, out of them the degradation of the sample and the availability of the "ante mortem reference data" (AMRD) play the major role.
Authors and Affiliations
Consoloni Lara, Recchia Elisa, SorçaburuCilieri Solange, Gobbo Chiara, Fattorini Paolo, Edalucci Elisabetta
Keywords
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- EP ID EP635433
- DOI 10.32474/PRJFGS.2018.01.000108
- Views 229
- Downloads 0
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