Placebo effect in treatment of pain associated with venous leg ulcers
Journal Title: Postępy Dermatologii i Alergologii - Year 2005, Vol 22, Issue 6
Abstract
Venous leg ulcers constitute a major therapeutic and social problem. This chronic recurrent condition concerns mostly elderly patients, often suffering from a number of other diseases, thus adding to their disability. Lower leg pain is the most common subjective symptom of the disease. Ever higher doses of strong analgesic drugs are commonly used in treatment of leg ulcers, sometimes with poor pain relief. Own observations reveal the possibility of alleviating this pain with administration of placebo. The probable mechanism of analgesic action of placebo, associated with patient's belief in efficacy of administered drug, lies in stimulation of release of endogenous opiates and activation of reward centers within the central nervous system. Currently many studies are conducted concerning possible utilization of this psychological mechanism in treatment of various pain syndromes.
Authors and Affiliations
Ewa Joss-Wichman, Anna Zalewska-Janowska
Keywords
Related Articles
- EP ID EP83611
- DOI -
- Views 56
- Downloads 0
Alergia pokarmowa. Część II – Ryby
W pracy omówiono następujące zagadnienia: 1) epidemiologię alergii na ryby z uwzględnieniem osobliwości objawów u dzieci i dorosłych; 2) wziewną alergię na ryby; 3) skryte źródła ryb; 4) obraz kliniczny alergii na ryby;...
The new look on the latex allergy; risk groups, clinical manifestation, diagnosis, prevention
In this review we present the newest data concerning the prevalence of latex allergy in high-risk populations in highly developed countries and in Poland. The prevalence of latex allergy in Western Europe and in the USA...
Współczesne poglądy na etiopatogenezę łysienia plackowatego
Łysienie plackowate (alopecia areata – AA) jest częstą jednostką chorobową, stanowiącą ok. 2% wszystkich dermatoz. Występuje zarówno u ludzi, jak i u innych ssaków, może pojawić się w każdym wieku. Główne odmiany klinicz...
The role of mastocytosis in anaphylaxis
The elevated basal serum tryptase, which is accompanied in 7-8% of cases of mastocytosis has been shown the important risk factor of anaphylactic reactions in patients with hymenoptera venom hypersensitivity. Mastocyto...
Verrucous carcinoma - review of clinical and histological manifestations
Aim: The presentation of the clinical and histopathological characteristics, the differentiation and treatment of verrucous cancer (Ackerman’s cancer), which constitutes the rare and poorly known oncological unit. Mathe...