Placental ischemia modified albumin may be a marker of oxidative stress in pre-eclampsia
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 1
Abstract
Preeclampsia is a known ischemic condition. It increases the maternal oxidative stress. Babies born to the preeclamptic mothers may have appropriate birth weight and gestational age. Studies about the oxidative stress in those apparently healthy babies are scarce. 45 preeclamptic and 40 age matched control mothers were selected for the study. Ischemia modified albumin [albumin cobalt binding assay] and protein carbonyl [DNPH method] were estimated in them. Significant rise of Ischemia modified albumin was found in cord blood of babies born to preeclamptic mothers.(p<0.0001 ). No significant alteration was found in cord blood protein carbonyl levels between case and control groups. Babies born to preeclamptic mothers were suffering from oxidative stress. Those babies should be kept under observation and should be supplemented by antioxidants. Keywords: Cord blood, Ischemia modified albumin, protein carbonyl, Preeclampsia
Authors and Affiliations
Kar Kaushik, Sinha Satwika
Keywords
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