Placental pathology in low birth weight babies a prospective observational study
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 2
Abstract
Introduction Low birth weight LBW babies are more common in developing countries like India The placenta is an organ which connects fetus to mother during intrauterine life Any change in the mother reflects on placenta and thus on the fetusMaterials and Methods In this study placenta from LBW were evaluated We included 50 fresh placentae Gross examination including weight shape thickness fetoplacental ratio was calculated Later histomorphological study of all placentae was done The extent of placental lesions which can influence the birth weight of the baby or adverse fetal outcome were correlatedResults Out of 50 placentae studied there was significant reduction in placental weight and dimension Irregular shape of placenta was seen in 13 cases and most of the plscenta 27 cases showed paracentral insertion of umbilical cord On gross infarction 56 subchorionic fibrin 64 intervillous fibrin 52 were noted On microscopy cytotophoblast hyperplasia 52 stomal fibrosis 48 fibrinoid necrosis 100 synnctial knots 3268 hypovascular villi 44 were notedConclusion All major gross and microscopic changes in the low birth weight placentas pointed towards reduced blood flow to the placenta resulting in chronic placental insufficiency The severity of placental abnormalities expressed as cumulative number of placental lesions is a significant risk factor for LBW babies Morphological examination of the placenta conducted in the present study proved to be a useful adjunct to the clinical examination in finding the pathogenetic mechanisms during pregnancy resulting in LBW babies and can be helpful in the planning and management of future pregnanciesKeywords Placental examination Low birth weight babies Pregnancy Fetoplacental ratio
Authors and Affiliations
Chaithra R Jadhav, Banushree C Srinivasamurthy, Ramchandra V Bhat, Vinita Agrawal, Harendra Kumar
Keywords
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- EP ID EP475483
- DOI 10.18231/2394-6792.2018.0034
- Views 31
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