Plasma Exchange as a Therapeutic Modality in a Rare Case of Cryptogenic New Onset Refractory Status Epilepticus (NORSE)
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 7
Abstract
Refractory Status Epilepticus (RSE) not responding to any therapy and not associated with any aetiology has been termed as New Onset Refractory Status Epilepticus (NORSE). Guidelines for optimal management of cryptogenic NORSE are not clearly defined so far in the literature. Other than common medication, use of high-dose steroids, IV immune globulins, and plasma exchanges in NORSE of unknown aetiology have been scarcely described. Immunomodulatory therapy like plasmapheresis is based on the fact that a pathological substance exists in the plasma that contributes to the disease process and its symptoms, which gets removed. We report a case of young female patient diagnosed as NORSE who responded to treatment with plasma exchange after becoming refractory to antiepileptic therapy and treatment with anaesthetic agents for recurrent seizers.
Authors and Affiliations
Manisha Shrivastava, Smita Chouhan, Seema Navaid Navaid
Keywords
Related Articles
- EP ID EP354363
- DOI 10.7860/JCDR/2017/29878.10292
- Views 76
- Downloads 0
Achondroplasia with Polydactyly: A Case Report
An eight-year-old girl child reported to the Department of Oral Medicine and Radiology with the chief complaint of unerupted permanent teeth for past two years. The child presented features like disproportionately short...
Influence of Different Thickness of Mineral Trioxide Aggregate, Resin Modified Glass Ionomer Cement and Intermediate Restorative Material on Sealing Ability of Root End Fillings: An in vitro Study
Introduction: A wide variety of root end filling materials has been tried, though the biocompatibility and sealing ability have been always in question. Hence, the latest innovation towards better sealing materials like...
Surgical Management of Root Canal Perforation Aided by CBCT Scan
ABSTRACT This study describes the surgical management of two Root Canal Perforations (RCP) in maxillary incisors aided by CBCT scans. In the first case, a patient was referred for retreatment due to a history of overfill...
Journey from Fighters to Survivors: Quality of Life and Mental Status in Cancer Patients in a Rural Tertiary Care Hospital
ABSTRACT Introduction: Cancer is a major public health burden in India. Though modern medicine has made tremendous advancements in the treatment of cancers, still morbidity and mortality remain high. It affects different...
Prevention of Severe Tongue Biting in a Mentally Challenged Patient: A Clinical Report
ABSTRACT Orofacial dysfunctions and habits are the main factors which influence the development of malocclusion and perioral disease. In this context, Orthodontics, a field of Dentistry, is closely associated with the d...