Platelet Hyperaggregation and Morphological Changes By Electron Microscopy in Simulated Dive
Journal Title: Haematology International Journal - Year 2018, Vol 2, Issue 1
Abstract
Dysbaric osteonecrosis and electroencephalogram (EEG) disturbances prompted the previous studies already submitted at Argentine Society of Haematology on the Scientific Meeting at 1982 and on the First Haemotherapy and Immuno-Haematology Argentine Congress at Buenos Aires in 1986. We will describe the study of platelet aggregation and platelet morphological changes by electron microscopy before and after of simulated dive in hyperbaric chamber without the addition of aspirin (ASA). 1.1. Materials and Methods: One hundred thirty (130) divers were studied at the Argentina Navy Submarine and Diving School (AA), in groups of ten (10) during the training courses required by the AA. Air was used as the breathing gas and all the dives were at a max depth of 39 meters (4.9 ATA- Absolute atmospheres) with a decompression was made according to US Navy Decompression Tables in use in the AA. First decompression stop at 6 meters (1.6 ATA) for 10 minutes and the second stop at 3 meters (1.3 ATA) for 25 minutes. Partial pressure of oxygen (Pp O 2) remained constant at the bottom to 1.03 ATA and partial pressure of carbon dioxide (Pp CO2) below 0,025 ATA. Blood was obtained in sodium citrate Na 3.2% at a rate of 1:9 citrate / blood. 1.2. Conclusion: We found that the simulated dive in vivo produces hyper aggregation and morphological changes in platelet in divers who did not take ASA.
Authors and Affiliations
García de Paoletti D
Keywords
Related Articles
- EP ID EP291053
- DOI -
- Views 115
- Downloads 0
Extramedullary Multiple Myeloma in the Kidney: A Case Report
Extramedullarymyeloma (EMM) is defined by the presence of plasma cells outside the bone marrow in a patient with multiple myeloma (MM). EMM is classified under four headings as bone-associated plasmacytoma, extramedullar...
Knowledge, Perception and Opinion of Health Workers on Bone Marrow Transplantation in Nigeria
1.1. Background: Bone marrow transplantation (BMT) or haematopoietic stem cell transplantation (HSCT) is a procedure used to cure haematopoietic malignancies, poorly functioning haematopoietic or immune system and geneti...
Differential Correlation between Foetal Haemoglobin and Full Blood Count Based on Inherited Haemoglobin Type; A Cross-Sectional Study in Cape Coast, Ghana
1.1. Background: Foetal haemoglobin (Hb F) has been shown to modulate the severity of sickle cell anaemia (SCA). However, there is scarcity of data on the impact of Hb F levels in other inherited haemoglobin variants. Th...
Physicians’ Opinion on the Practice of Exchange Blood Transfusion for Treatment of Stroke in Sickle Cell Anaemia
1.1. Background: The current most effective preventive as well as therapeutic modality for stroke in sickle cell anaemia (SCA) is the use of exchange blood transfusion (EBT) in a chronic transfusion program. The challeng...
The Epidemiology of Leukaemia in Zimbabwe: A Ten Year Retrospective Study
1.1. Background: Haematological malignancies are defined as primary cancers of blood cells. Leukaemia constitutes more than fifty-five percent of haematological malignancies. The epidemiology of leukaemia in Zimbabwe is...