Platelet Rich Fibrin- Evolution, Preparation and its Clinical Implications
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2018, Vol 6, Issue 11
Abstract
Platelet Rich Fibrin, a second generation platelet concentrate is an autologous leukocyte, cellular and fibrin matrix. It consists of an assembly of cytokines, glycanic chains and structural gylcoprotein’s enmeshed between a slowly polymerized fibrin network. It is free of any anticoagulant or other artificial biochemical modifications. It was first developed by Choukroun et al. (2001) The scientific rationale behind the use of platelet preparations lies in the fact that the platelet α- granules are a reservoir of many growth factors that play a crucial role in hard and soft tissue repair mechanism.
Authors and Affiliations
Parul Chhabra, Pujit Chhabra, Amisha Kakkar, Mohit Kumar, Sushila Kumari
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