Platelet-Rich Plasma Injections In The Management Of Chronic Tendinopathies
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 5
Abstract
PRP injections have been proposed as a promising alternative for treating tendinopathies. Platelets release various cytokines and growth factors which promote angiogenesis, tissue remodeling, and wound healing. In this studyPRP prepared by drawing blood from patient, centrifuging it , prp(3 to 10 times of the whole blood) will be injected over pathological tendon site over maximum point of tenderness, followed by immobilization of the part for 3 days ,followed by eccentric loading exercise for 6 weeks and results assessed clinically,visual analogue scale at regular interval . PRP injections will be widely accepted by the patient as prepared from patients own blood and risk of adverse effect is minimal. Platelets have known roles in coagulation, inflammatory processes, and immunity modulation. Moreover, during degranulation , platelets release various cytokines and growth factors(vascular endothelial growth factors, platelet derived growth factors, transforming growth factors B, Insulin like growth factor 1 and hepatocyte growth factors) which promote angiogenesis, tissue remodeling, and wound healing Tendinopathies are chronic affections of the attachments of muscles to the bones.
Authors and Affiliations
Dr. L K Swamy, Dr. A K Mishra, Dr. B K Sadangi, Dr. S K Hota, Dr. S Patra
Keywords
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- EP ID EP597652
- DOI 10.9790/0853-1605084151.
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