PMNL Cell Phagocytosis Activity Alters with Poly-Herbal Formulation in Diabetic Patients
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2018, Vol 8, Issue 3
Abstract
One of the major complications of diabetes weakens the immune system, which puts the diabetic person at risk for difficult-to-treat and persistent infections and delayed healing of wounds, especially the feet. Phagocytosis by polymorphonuclear leucocytes (PMNL) is the first line of defense against any infection. Diabetics are more prone to long lasting infections due to several reasons, the most important of them is impaired phagocytosis. We evaluated the change in Phagocytosis activity by using of a poly-herbal formulation in diabetic patients, Subjects were divided into four groups, Group I (NH), were normal healthy subjects, Group II (DI), were diabetics, group III (TTD) was tolbutamide treated diabetic patients, group IV (HFTD), were diabetic patients receiving combination herbal formulation in the, dosage of 5 g. /Day for 4 weeks. The result was exciting with prescribed formulation since it was found to be effective in the correction of all parameters related to phagocytosis , which are found to be disturbed in diabetic patients leading to an array of persistent infection . The present study could be proved an excellent immunopotiator will be a boon for diabetic patients in the near future for the management of diabetic complication.
Authors and Affiliations
Mohammad Nadeem Khan
Keywords
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