Polcalcins as pollen panallergens in allergic rhinitis
Journal Title: Romanian Journal of Rhinology - Year 2016, Vol 6, Issue 21
Abstract
Polcalcins are highly cross-reactive calcium-binding allergen components specifically expressed in pollen from trees, grasses and weeds. The grass allergen component rPhl p 7, a recombinant non-glycosylated calcium-binding protein of 2-EF-hand type, is the most cross-reactive polcalcin and may be used as a polcalcin biomarker of IgE-mediated hypersensitivity. Polcalcin sensitization, which appears to be linked to geographical factors, level and time of pollen exposure, has to be assessed in allergic rhinitis patients with multiple pollen sensitizations and may be useful for a better targeted prescription of allergen immunotherapy.
Authors and Affiliations
Florin - Dan Popescu, Mariana Vieru
Keywords
Related Articles
- EP ID EP463267
- DOI 10.1515/rjr-2016-0002
- Views 57
- Downloads 0
Sinonasal inverted papilloma – what’s new
Inverted or Schneiderian papilloma is a locally aggressive benign tumor with strong recurring tendency and a high potential to transform into a malignant squamous cell carcinoma. Although the clinical characteristics of...
A safe way to find the posterior ethmoidal cells: navigation with cottonoid
BACKGROUND. Functional endoscopic sinus surgery (FESS) is a reliable option in the treatment of sinus pathology, but the presence of the anatomical variant and difficult cases like massive polyposis or revision FESS can...
An unusual combined parotideal and neck abscess - Case report
Cervical and parotideal abscess is a rare finding in all populations and even more so in the paediatric population. The antibiotic resistance of the bacteria that cause these diseases can make it very dangerous. We prese...
Primary sinonasal mucosal melanoma – Case report and literature review
BACKGROUND. Primary sinonasal mucosal melanoma is a rare tumor with a poor survival rate. There is an inherent difficulty in diagnosing these lesions, especially because their complex anatomic locations and symptoms can...
Acoustic rhinometry and rhinomanometry as objective tools for the assessment of nasal patency in nasal septal surgery
BACKGROUND. Septal deviations are usually diagnosed by a patient’s subjective complaint of nasal stuffiness and a physical examination by the otorhinolaringologist. The decision for surgery is not always based on objecti...