POLYCYSTIC OVARIAN SYNDROME : UNDERSTANDING THE ENDOCRINOLOGICALPARADIGM
Journal Title: PARIPEX-Indian Journal of Research - Year 2018, Vol 7, Issue 5
Abstract
Endocrine and metabolic dysfunctional pathways of androgen synthesis have all been demonstrated to play a role in the pathophysiology of PCOS. So we did comparative study of endocrinological pattern between PCOS infertile case and non PCOS infertile control. Approximately 50% of all women with PCOS are obese but irrespective of the presence of obesity, these women are frequently insulin resistant. Many hormonal pattern are altered in this metabolic condition responsible for primary infertility and is corroborated with hyper androgenic state as we found in our study. Identification of this clinical state could lead to better clinical outcome regarding infertility and prevention of long term Metabolic and cardiovascular complication. Conclusion: Polycystic Ovarian syndrome should be interpreted as metabolic syndrome showing the tip of iceberg in context to immediate gynecological and long term metabolic complication.
Authors and Affiliations
Dhiraj Kishore, Amita Diwakar
Keywords
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