Polyherbal Extract of Ocimum Gratissimum and Gongronema Latifolium on Reproductive Functions in Alloxan Induced Diabetic Male Rats
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 4
Abstract
Background: Reproductive functions are impaired in diabetes mellitus. Polyherbal extracts from ocimum gratissimum and gongronema latifolium extracts on reproductive hormones and sperm parameters were studied in alloxan induced diabetic rats. Materials and Methods: Twenty five adult male albino rats were used in the study. Twenty rats were made diabetic using 100 mg/kg body weight of alloxan monohydrate (intraperitoneal injection). The rats were divided into five groups I (control), II (diabetic control), III, IV and V. The rats were treated with 200mg/kg of ocimum gratissimum (group III), 200mg/kg of gongronema latifolium (group IV), and 200mg/kg per extract of ocimum gratissimum and gongronema latifolium (group V) for 21 days. Results: The rats treated with polyherbal extracts showed significantly reduced levels of FSH, LH, testosterone, sperm count, sperm motility, sperm morphology and viability. The same results was obtained in rats treated with gongronema latifolium (200mg/kg) except in rats treated ocimum gratissimum extract (200mg/kg) that showed elevated testosterone levels. Conclusion: These findings showed that polyherbal treatment from ocimum gratissimum and gongronema latifolium do not restore reproductive functions in alloxan induced diabetic rats
Authors and Affiliations
Agbai Emmanuel Onuka
Keywords
Related Articles
- EP ID EP205743
- DOI -
- Views 151
- Downloads 0
Scrotal Emergencies-Two case reports on Scrotal Exploration Scenario
This case report evaluates the management of acute scrotal emergency in two similar cases with presenting complaints and different outcomes post-scrotal exploration. One case of young male discusses the eventual outcome...
Study of Contraceptive Practices and Reasons For Not Accepting Contraceptives
Background: Family planning is helpful in population control, poverty reduction,human development and better position of girls.The extent of acceptance of contraceptive methodazs still varies within societies. The factor...
Long-term follow up of talus fractures; the surgical treatment outcome of 30 cases after 5 years
Talus fractures are rare and usually the result of high-energy trauma. These fractures compromise motion of the foot and ankle and result in severe disability. Therefore a satisfactory clinical outcome remains a challeng...
Monitoring and Analysis of Adverse Drug Reactions in A Private Tertiary Care Hospital
The detection of ADRs has become increasingly significant because of introduction of a large number of potent drugs in the last two or three decades, especially antimicrobials. ADRs could be monitored through active moni...
Perinatal Outcome in Pregnancies with Polyhydramnios
Polyhydramnios is defined as an amniotic fluid volume of more than 2000 ml, is confirmed ultrasonographically by single vertical pocket more than 8cm or amniotic fluid index more than 25 cm. Polyhydramnios complicates 0....