The objective of this study was to characterize the baseline circadian rhythm of testosterone levels in hypogonadal men. A total of 859 baseline profiles of testosterone from hypogonadal men were included in this analysi...
MicroRNAs (miRNAs) are ~22 nucleotide long, noncoding, endogenous RNA molecules which exert their functions by base pairing with messenger RNAs (mRNAs), thereby regulate protein-coding gene expression. In eukaryotic cell...
Recent advances in the synthesis of endocannabinoid-related ligands for the period 2001–2004 are covered in this review. During this period the first solid phase synthesis of anandamide (AEA) analogs was develope...
In the kidney, human organic cation transporters (OCTs) and multidrug and toxin extrusion proteins (MATEs) are the major transporters for the secretion of cationic drugs into the urine. In the human kidney, OCT2 mediates...
We have advocated the idea of agonist therapy for treating cocaine addiction. This strategy involves administration of stimulant-like medications (eg, monoamine releasers) to alleviate withdrawal symptoms and prefent rel...
EP ID EP681860
DOI 10.1208/aapsj070236
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How To Cite
Diane R. Mould, Peter L. Bonate (2005). Population pharmacokinetics: A memorial tribute to Lewis Sheiner. The AAPS Journal, 7(2),
-. https://europub.co.uk/articles/-A-681860
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Modeling Testosterone Circadian Rhythm in Hypogonadal Males: Effect of Age and Circannual Variations
The objective of this study was to characterize the baseline circadian rhythm of testosterone levels in hypogonadal men. A total of 859 baseline profiles of testosterone from hypogonadal men were included in this analysi...
Therapeutic MicroRNA Strategies in Human Cancer
MicroRNAs (miRNAs) are ~22 nucleotide long, noncoding, endogenous RNA molecules which exert their functions by base pairing with messenger RNAs (mRNAs), thereby regulate protein-coding gene expression. In eukaryotic cell...
Further advances in the synthesis of endocannabinoid-related ligands
Recent advances in the synthesis of endocannabinoid-related ligands for the period 2001–2004 are covered in this review. During this period the first solid phase synthesis of anandamide (AEA) analogs was develope...
Organic Cation Transporter OCTs (SLC22) and MATEs (SLC47) in the Human Kidney
In the kidney, human organic cation transporters (OCTs) and multidrug and toxin extrusion proteins (MATEs) are the major transporters for the secretion of cationic drugs into the urine. In the human kidney, OCT2 mediates...
Dual dopamine/serotonin releasers as potential medications for stimulante and alcohol addictions
We have advocated the idea of agonist therapy for treating cocaine addiction. This strategy involves administration of stimulant-like medications (eg, monoamine releasers) to alleviate withdrawal symptoms and prefent rel...