POPULATION PHARMACOKINETICS OF PACLITAXEL IN INDIAN CANCER PATIENTS USING NONMEM
Journal Title: European Journal of Biomedical and Pharmaceutical Sciences - Year 2017, Vol 4, Issue 8
Abstract
Population pharmacokinetics is the study of the sources and correlates variability in plasma drug concentrations between individuals representative of those in whom the drug will be used clinically when relevant dosage regimens are administered (Aarons, 1991). Population pharmacokinetics seeks to discover which measurable pathophysiological factors cause changes in the dose-concentration relationship and to what degree so that the appropriate dosage can be recommended.
Authors and Affiliations
Dr. Sandhyarani G.
Keywords
Related Articles
- EP ID EP628989
- DOI -
- Views 139
- Downloads 0
ASSOCIATION OF HYPERURICEMIA WITH PREECLAMPSIA: IS SERUM URIC ACID A GOOD PREDICTOR OF PREECLAMPSIA ? KHARTOUM, SUDAN
Background: Preeclampsia is an important cause of fetal and maternal mortality and morbidity worldwide. Hyperuricemia is a common finding in preeclampsia. Serum uric acid measurement is widely used and investigated for t...
ANTIOXIDANT PROFILES OF ALCOHOLIC TINCTURES FROM HETEROTIS ROTUNDIFOLIA (SM.) JACQ.-FÉL. (MELASTOMACACEAE) BY DPPH RADICAL TRAPPING
Phytophenols are widely distributed in the vegetable kingdom. This is the reason why, for the first time, we evaluate the phenolic compound content and the antioxidant profile Heterotis rotundifolia alcoholic tinctures,...
COMPARISON BETWEEN HALOPERIDOL AND RISPERIDONE IN DEVELOPMENT OF METABOLIC SYNDROME IN INDIAN PATIENTS
Introduction: It is well known that anti-psychotics are associated with many side effects. One of the significant adverse drug reactions among these is weight gain and development of metabolic syndrome. In this study, we...
EVALUATION OF ANTIOXIDANT POTENTIALS OF METHANOLIC EXTRACTS OF OCIMUM GRATISSIMUM AND VERNONIA AMYGDALINA
Oxidative stress has been identified as the root cause of the development and progression of several diseases. Supplementation of exogenous antioxidants or boosting endogenous antioxidant defenses of the body is a promis...
MICROBIAL BIOFILM IMPACT IN FOOD INDUSTRY AND PREVENTION STRATERGIES
Certain bacteria develop a fortress or biofilm in the environments they colonize which provides shield from antimicrobials and other sanitation process. A biofilm is developed in planktonic (and free/stand-alone) cells i...