POST-OPERATIVE SORE THROAT: INCIDENCE AND SEVERITY AFTER NEBULIZATION WITH KETAMINE AND SALINE
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 26
Abstract
BACKGROUND Postoperative sore throat is a common complication of general anaesthesia with endotracheal intubation that affects the patient’s satisfaction after surgery. Post-operative sore throat (POST) following tracheal intubation is due to the trauma to the airway mucosa. The reported incidence of post-operative sore throat varies from 21%- 65%. Our study was undertaken to assess the efficacy of ketamine nebulization for attenuating POST in patients undergoing elective surgeries under general anaesthesia with endotracheal intubation. Ketamine is N methyl D aspartate (NMDA) receptor antagonist, involved in anti-nociception and antiinflammatory cascade. METHODS 200 patients aged 20-60 years belonging to ASA PS I-II, scheduled for elective surgeries under general anaesthesia with endotracheal intubation satisfying the inclusion criteria were assigned into 2 groups of 100 each. Group 1: Patients received nebulization with 50 mg ketamine in 4 ml normal saline. Group 2: Patients received 5 ml normal saline; they were given nebulization 10 minutes prior induction. RESULTS In our study, the overall incidence of POST was less in ketamine group when compared to saline group. Our study also revealed that duration of intubation is a significant risk factor for postoperative sore throat in patients undergoing surgeries under general anaesthesia with endotracheal tube. CONCLUSIONS From our study we conclude that ketamine nebulization had significant impact on both reductions in incidence as well as severity of postoperative sore throat in patients undergoing surgeries under general anaesthesia with endotracheal intubation.
Authors and Affiliations
Krishnanakutty Saradas Asha, Padmavathi Padmavathi
Keywords
Related Articles
- EP ID EP668485
- DOI 10.18410/jebmh/2019/367
- Views 84
- Downloads 0
A RARE CASE OF ALL PRESENTING WITH UNILATERAL TONSILLAR ENLARGEMENT- A CASE REPORT
Acute Lymphoblastic leukemia (ALL) is more common in children and least in adults. About 6,000 people are diagnosed with ALL each year. Children account for two-thirds of these cases. ALL represents about 15% of all mali...
A COMPARATIVE STUDY OF TOTAL SERUM CHOLESTEROL AND HDL CHOLESTROL IN PREMENOPAUSAL AND POSTMENOPAUSAL WOMEN IN AND AROUND BARPETA TOWN, ASSAM
INTRODUCTION After menopause abnormal lipid levels and a relatively high incidence of coronary heart disease show a possible relationship among estrogens, normal lipid level and a relative immunity to CHD. A reduction of...
A STUDY TO ESTABLISH ASSOCIATION OF HYPERGLYCEMIA AND INPATIENT MORTALITY IN PATIENTS WITH UNDIAGNOSED DIABETES MELLITUS
The aim of this study was to establish the prevalence, survival, and outcome of patients presented with in-hospital hyperglycemia in which there is prior history of diabetes and without a history of diabetes. We reviewed...
REPAIR OF LARGE SKULL BASE DEFECT FOLLOWING EXCISION OF BASALOID SQUAMOUS CELL CARCINOMA OF MAXILLO-ETHMOID REGION: A CASE REPORT
AIM: To present a case of basaloid squamous cell carcinoma of maxillo-ethmoid region with intracranial extradural extention and its surgical management including repair of the skull base defect. MATERIAL: A 30 year femal...
USE OF TWO STEP FOOT-REST UTILIZED FOR MAKING LITHOTOMY POSITION FOR ANORECTO-UROGENITAL SURGERIES IN INFANT PATIENTS WITH EASY APPROACH FOR ANAESTHESIOLOGIST AS WELL AS FOR SURGEON
This study was carried out in 40 infant patients with the aim is to provide optimal position for better surgical access and better access for anaesthesiologist regarding patient’s monitoring while minimizing manpower wit...