Post operative wound infections: pattern of bacterial pathogens and their antibiotic sensitivity in a tertiary care hospital of north India
Journal Title: INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY - Year 2017, Vol 22, Issue 3
Abstract
Background: Surgical site infection (SSI) is defined as an infection that occurs at an incision site within 30 days after surgery. Postoperative wound infections have been an important cause of morbidity and cost burden for the patients. Aim and Objectives: To isolate and identify the bacteria causing postoperative wound infections and to determine the antimicrobial susceptibility pattern. Materials and Methods: One hundred and twenty pus samples and wound swabs were collected from clinically suspected post-operative wound infection in Maharishi Markendeshwar Institute of Medical Sciences and Research, Mullana, Ambala from January 2014 to December 2014. The samples were processed as per standard guidelines. Antimicrobial susceptibility testing was performed as per CLSI guidelines. Results: Out of 120 pus samples and wound swabs, 44 samples (36.7%) were culture positive. 76 samples (63.3%) were culture negative. The common organisms isolated were Staphylococcus aureus 16 (36.3%), Escherichia coli 09 (20.4%), Klebsiella pneumoniae 8 (18.1%) and Pseudomonas aeruginosa 7(16%). Most of the Staphylococcus aureus exhibited resistance to penicillin, cefoxitin and aminoglycosides, and 100% sensitivity to vancomycin and gram negative bacilli showed resistance commonly to first and second line antibiotics. Conclusion: Staphylococcus aureus was the most frequently isolated pathogen from post- operative wound infections. Antibiotic susceptibility pattern of various isolates help to assist the clinician in appropriate selection of empirical antibiotics especially against hospital acquired infections.
Authors and Affiliations
Natasha Sawhney, Rahul Prabhas, Varsha A Singh
Keywords
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