POSTERIOR CRANIAL FOSSA LESIONS- A CLINICOPATHOLOGICAL CORRELATIVE STUDY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 64
Abstract
BACKGROUND Posterior cranial fossa houses the cerebellum and brainstem that contains all cranial nerve nuclei and many afferent fibre tracts that connect the brain with the rest of the body. Early diagnosis of posterior fossa lesions is vital to prevent complications like herniation and brainstem compression that is invariably fatal. The present study is an attempt to collect the demographic profile and types of posterior fossa lesions. We also assessed the extent of correlation between clinical and radiological diagnosis and the diagnosis on histopathology. MATERIALS AND METHODS A retrospective analysis of 75 biopsy specimens from posterior fossa lesions received in the Department of Pathology, Government Medical College, Trivandrum, over a 3-year period was done. The data collected included age, sex, site of lesion, clinical presentation, radiological and histopathological diagnosis. The diagnosis in all the cases were made on haematoxylin and eosin stained slides of processed tissue. RESULTS We received a total of 75 cases of posterior fossa lesions in the 3-year period. Most of the lesions occurred in the age group between 50 and 59 years (20%) followed by 0 to 9 years (16%). The male-to-female ratio observed was 1.33: 1. The nonneoplastic lesions observed were cerebellar abscess and arachnoid cyst. In adults, the most common tumour was Schwannoma, while in children it was medulloblastoma. Agreement between clinical and histopathological diagnosis was observed in 64% of the cases. CONCLUSION Posterior fossa lesions affect all age groups, especially paediatric age group with a male predominance. Clinical pathological correlation and grading are significant pertaining to the choice of treatment modality for the patient.
Authors and Affiliations
Priya V. S, Surupa Susan Kurien
Keywords
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- EP ID EP231493
- DOI 10.14260/Jemds/2017/1009
- Views 72
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