Postpartum adiponectin changes in women with gestational diabetes
Journal Title: Annals of Agricultural and Environmental Medicine - Year 2014, Vol 21, Issue 4
Abstract
[b]introduction and objective[/b]. Current literature provides contradictory information on the role of adiponectin (AdipoQ) in the course of gestational diabetes mellitus (GDM) and the changes after delivery. The aim of the study was to measure AdipoQ concentration in blood of women with GDM, and to conduct a comparative analysis of AdipoQ concentrations in gestation at 3 and 12 months after delivery. [b]material and methods[/b]. The study group consisted of 50 women diagnosed with GDM between 24 and 28 weeks of gestation. Three months after delivery, 41 women underwent further tests, while 12 months after delivery 30 patients. All patients underwent clinical and laboratory evaluation at GDM diagnosis at 3 and 12 months after delivery. Laboratory evaluation included fasting glucose, fasting insulin, OGTT and lipid parameters in serum. Serum AdipoQ concentration was measured at GDM diagnosis as well as at 3 and 12 months after delivery. [b]results[/b]. AdipoQ concentrations did not differ significantly between the groups during gestation (p=0.7054) and 3 months after delivery (p=0.9732), while a significant rise was observed 12 months after delivery, compared to the values during pregnancy (p=0.0006). AdipoQ in the GDM group 12 months after delivery inversely correlated with fasting glucose and 2-hour post-load plasma glucose after a 75-g oral glucose tolerance test (r=-0.37 * ; p<0.05 and r=-0.42, p<0.05, respectively). [b]conclusions[/b]. An increased level of AdipoQ after delivery in the comparison to women with GDM may be a marker for reversibility of carbohydrate metabolism disorders, while a negative correlation between AdipoQ and glucose levels suggests that this parameter may be a predictor In the future of disturbances in glucose tolerance in women with GDM.
Authors and Affiliations
Beata Matyjaszek-Matuszek, Monika Lenart- Lipińska, Jolanta Kowalczyk-Bołtuć, Sławomir Wożniak, Tomasz Paszkowski
Keywords
Related Articles
- EP ID EP80893
- DOI -
- Views 116
- Downloads 0
Assessment of microbiological cleanness of selected medicinal herbs in relations to the level of resource fragmentation
Herbs are commonly used in the food and pharmaceutical industries. Their vast use is connected with their antibacterial or antioxidising properties, as well as numerous pro-health properties. The aim of the presented res...
Hantavirus RNA was not detected in Dermacentor reticulatus ticks
A total of 190 [i]Dermacentor reticulatus[/i] ticks (80 males, 110 females) collected on the territory of Ostrów Lubelski, Suchawa, Zalutyń and Kazimierz Dolny (Lublin Province, eastern Poland) were examined by reverse t...
Biological and environemntal conditionings for a sperm DNA fragmentation
The objective of the presented study was determination of the effect of selected agents on sperm DNA fragmentation – superoxide dismutase in seminal plasma, the patients’ age, and burdening with the tobacco smoking habit...
Physical activity in perimenopausal women
[b]Introduction.[/b] The menopausal age of women is characterized by a high probability of health problems related with oestrogen deficiency and reduced ovarian hormonal activity. The most significant element in the ther...
Symptoms of depression among adults in rural areas of western Poland
[b]Objective[/b]. To measure the intensity of depressive symptoms in the populations residing in rural areas of western Poland, and to delineate the putative association between the intensity of depression and selected s...