Potential for misdiagnosis in a rare entity: A case report of kimura’s disease
Journal Title: MedPulse -International Medical Journal - Year 2017, Vol 4, Issue 2
Abstract
Kimura disease (KD) is a rare form of chronic inflammatory disorder involving subcutaneous tissue, predominantly in the head and neck region and frequently associated with regional lymphadenopathy and/or salivary gland involvement. Cytologically, the varied spectrum of findings in KD range from nonspecific lymphadenitis to features simulating many other lesions. Imaging is often not diagnostic as they give nonspecific variable appearance, though CT and MRI are helpful in delineating the extent of disease. Differentials to be excluded on histopathological examination are angiolymphoid hyperplasia with eosinophilia, Hodgkin's lymphoma, angioimmunoblastic T-cell lymphoma, Langerhan's cell histiocytosis and parasitic lymphadenitis. Due to variable involvement of multiple lymph nodes, salivary glands and subcutaneous tissue, a multimodal line of investigation is usually required. However, there are several pitfalls and final diagnosis requires an excision biopsy and histopathological examination. We present a case of a 42 year old male patient with involvement of subcutaneous tissue, lymph nodes as well as salivary gland. Imaging and cytologic examination were suggestive of vascular lesion and reactive lymphadenitis respectively. Final diagnosis was reached only after histopathologic examination.
Authors and Affiliations
Shubham Swasti, Monika Singh, Pratibha Maan, Manju Kaushal, Minakshi Bhardwaj
Keywords
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