Potential of Rubus Ulmifolius Schott Supplementation in the Attenuation of Sucrose-Induced Hyperglycemia, Dyslipidemia and Liver Oxidative Damage in Rats
Journal Title: Journal of Diabetes and Obesity - Year 2016, Vol 3, Issue 2
Abstract
Metabolic syndrome is associated with several disorders, including hypertension, diabetes, hyperlipidemia as well as cardiovascular diseases and stroke. The purpose of the present study was to investigate the preventive effect of Rubus ulmifolius Schott extract (E) on hyperglycemia, hyperlipidemia and liver oxidative stress in rats fed a high-sucrose diet. Male Wistar rats (n = 21) weighing 115 ± 3 g were used in this experiment. For induction of MS, fourteen rats were given free access to 60% sucrose in drinking water and seven rats received water for 3 weeks. After this induction phase, rats were assigned to three equal-weight groups as follows: 1) C: rats were kept on standard pellet diet. 2) HSD: rats were kept on high-sucrose diet containing 60% sucrose for 3 weeks. 3) HSD + E: rats were kept on HSD and orally administered 300 mg/kg of extract by stomach tube once daily for a period of 3 weeks.
Authors and Affiliations
madani zohra
Keywords
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- EP ID EP417842
- DOI 10.15436/2376-0494.16.1141
- Views 104
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