POTENTIAL ROLE OF GROWTH AND DEFFERENTIATION FACTORS IN PERIODONTAL REGENERATION
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2018, Vol 7, Issue 10
Abstract
Growth factors are polypeptide hormones or biological factors. They mediate many cellular processes necessary for the various stages of growth, induction of phenotypic expression, and even the metamorphosis of totipotent germ cells into pluripotent stem cells.[1,2] A totipotent germ cell is a single cell that can recapitulate or repeat development, demonstrating the capacity to develop and differentiate into a complete organism.[2,3] A pluripotent stem cell is “capable of differentiating into several different final differentiated types.”[3] When germ cells are cultured in certain polypeptide growth factors, they can be stimulated to transform into pluripotent stem cells. 2 Growth factors are also known to influence the growth rate of certain cancers.[4] Many tissues are mediated by growth factors: epithelium and endothelium; myocardium and neural tissue; cartilage, bone, and cementum; the more specialized types of connective tissue and blood: and the less specialized connective tissue replete with extracellular matrix, such as collagen and proteoglycans that surround other more highly developed tissues and organs.[1] Polypeptide growth and differentiation factors (GDFs) are classified as biological mediators that have demonstrated a significant role in stimulating and regulating the wound healing process. The growth factors associated with repair and regeneration coordinate important cellular processes such as:[1]
Authors and Affiliations
Ali Kadhim Jalil
Keywords
Related Articles
- EP ID EP628034
- DOI -
- Views 130
- Downloads 0
METABOLOMIC ANALYSIS AND THE APPLICATIONS FOR PROFILING AND CHARACTERIZATION OF TEA (CAMELLIA SINENSIS L.)
Metabolomic analysis is a study to determine as much as possible the metabolite in a system, in this case the tea plant. In general, metabolomic analysis is classified into targeted analysis and untargeted analysis. Meta...
ORAL GLUCOSE TOLERANCE TESTS WITH COMBINATION OF METHANOLIC EXTRACT OF AERIAL PARTS OF Bulbophyllum neilgherrense AND GLIBENCLAMIDE
Background: Bulbophyllum neilgherrense Wight is an epiphytic monocot belonging to the Orchidaceae family and found in Bangladesh and India. Since orchids have always been used in indigenous medicines, it was therefore of...
SYNTHESIS, IDENTIFICATION AND ANTIBACTERIAL EVALUATION OF SOME 1,3,4- OXADIAZOLES DERIVATIVE ON 1,8-NAPHTHYRIDINE RING
Several 1,8-naphthyridine derivative were prepared using Vilsmeier-Haack synthization. 2-chloro-3-formyl-1,8-naphthyridine was synthesized by reacting N-(pyridin-2-yl) acetamide with POCl3 in dimethylformamide. 1,8-napht...
TRANSFUSION SUPPORT IN PATIENTS UNDERGOING AUTOLOGOUS HEMATOPOIETIC STEM CELLS: LITERATURE REVIEW
Hematopoietic stem cell transplantation is often the only cure for a patient. There are several obstacles that they face during the whole process of seeking a donor: the remission of the disease to enable the procedure,...
ORAL GLUCOSE TOLERANCE TEST (OGTT) WITH A COMBINATION OF COLOCASIA ESCULENTA STEMS AND EICHHORNIA CRASSIPES AERIAL PARTS
Background: In previous experimental studies, it was observed that various parts of Colocasia esculenta (L.) Schott possess antihyperglycemic potential. The objective of the present study was to determine the antihypergl...