Potentiometric Determination of Cyclizine by PVC Membrane Sensor
Journal Title: Scholars Academic Journal of Pharmacy - Year 2016, Vol 5, Issue 10
Abstract
Abstract:The two ion-pair complex of Cyclizine (Cy) with sodium tetraphenyl borate (TPB) and Phosphotungstic acid (PT) was prepared and used for the construction of Cy-selective electrode. The electrode based on the Cy-PT ion-pair complex has a lower detection limit of 1.5 x 10-7 M in a linear concentration range of 3.5 x 10-7 – 1.0 x 10-2 M with a slope of calibration curve of 50.5 mV/decay. The selectivity coefficient was calculated with separate solution method dictates the high selectivity of the electrode over other tested ions. Keywords:Potentiometry, Cyclizine, ion-selective electrode, selectivity.
Authors and Affiliations
Seema Tomar
Keywords
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