Pre-Emptive Analgesic and Opioid Sparing Effect of Ketamine in Patients Undergoing Total Radical Mastectomy
Journal Title: International Journal of Research and Review - Year 2018, Vol 5, Issue 12
Abstract
Background: The present study has been undertaken to evaluate pre-emptive analgesic and opioid sparing effect of intravenous ketamine in patients undergoing total radical mastectomy. Method: Eighty female patients undergoing breast cancer surgery under general anesthesia, in a double-blinded, placebo controlled study were randomly divided into two groups of 40 patients each. Group K received ketamine 0.3mg/kg IV just before induction. Group C received normal saline as placebo. Result: Time to first analgesic dose (TFA) required was significantly delayed in ketamine as compared to placebo group. Statistically significant difference was seen in Visual analog score (VAS), Prince Henry score (PHS) and mean morphine consumption between ketamine and control group. Conclusion: This study proved that ketamine has a definitive role in reducing postoperative pain and has opioid sparing effect in patients undergoing modified radical mastectomy.
Authors and Affiliations
Shakti Datt Sharma
Keywords
Related Articles
- EP ID EP480937
- DOI -
- Views 73
- Downloads 0
Socio- Economic and Demographic Variables Impacting the Costing of Diabetes Mellitus in an Urban Slum in Mumbai
Although Diabetes mellitus (DM) is a common chronic disease in nearly all countries, India is on the brink of an epidemic of Diabetes Mellitus. It is an escalating problem in India and has major socioeconomic dimensions....
Innovative Practices in Chemical Engineering Teaching- a Brief Review
The chemical engineer has to deal with various interdisciplinary subjects such as mechanical engineering, environmental engineering, biotechnology etc. Many important subjects such as mass transfer, heat transfer, proces...
Corrosive Induced Gastric Outlet Obstruction in Children
Background: Patients with gastric outlet obstruction, secondary to corrosive ingestion admitted in pediatric surgery department from January 2005 to June 2016. Most common corrosive was sulphuric acid and it was taken ac...
Thermal Design of an Oil Fired Crucible Furnace using CFD Technique
Thermal design of a furnace could be complex and time consuming as it requires iterative calculations to arrive at expected operating temperature values of the various parts or segments of the furnace. A more accurate an...
Youths’ Participation in the Tourism Development at Sibolangit Natural Tourism Park
The objective of the research entitled Youths’ Participation in the Tourism Development at Sibolangit Natural Tourism Park was 1) to analyze youths’ participation in the tourism development at Sibolangit Natural Tourism...