Predicting Lamina Propria Invasion in Patients with Nonmuscle- invasive Bladder Cancer: Do RDW and NLR Really Work?
Journal Title: Üroonkoloji Bülteni - Year 2019, Vol 18, Issue 1
Abstract
Objective: To determine the role of preoperative neutrophil-to-lymphocyte ratio (NLR) and red cell distribution width (RDW) in predicting lamina propria invasion in bladder cancer. Materials and Methods: Eighty-eight patients with non-muscle-invasive bladder cancer were evaluated retrospectively. The patients were divided into those with Ta tumors (group 1: n=36) and those with T1 tumors (group 2: n=52). For each patient, white blood cell, neutrophil, and leukocyte counts and RDW values were evaluated. Results: NLR was significantly lower in patients with Ta tumors. In addition, NLR below 3.22 was associated with 80.6% probability of Ta disease. RDW sensitivity in Ta non-muscle-invasive bladder tumors was much higher compared to T1 tumors. RDW below 15.35 was associated with 94.4% probability of Ta disease. Conclusion: NLR and RDW are basic blood parameters that physicians can assess easily. Our results indicate that a combination of NLR and RDW can help clinicians predict lamina propria invasion in non-muscle-invasive bladder tumors.
Authors and Affiliations
Aykut Buğra Şentürk, Musa Ekici, Cemil Aydın, Mehmet Murat Baykam, Tuncay Taş, Ersan Arda, Basri Çakıroğlu
Keywords
Related Articles
- EP ID EP550854
- DOI 10.4274/uob.galenos.2018.1099
- Views 65
- Downloads 0
Evaluation of the Side Effect Profile of Intracavitary Bacillus Calmette-Guérin Treatment in Non-muscle-invasive Bladder Cancer
Objective: To reveal the association of side effect profiles seen in patients receiving intravesical bacillus Calmette-Guérin (BCG) immunotherapy for non-muscle-invasive bladder cancer (NMIBC) treatment with patient age...
A Rare Tumor: Small Cell Prostate Carcinoma Case Report
Prostate small cell carcinoma is a rare and aggressive tumor. They can be distinguished from classic prostate adenocarcinoma by features such as lack of prostate-specific antigen secretion, failure to respond to androgen...
Histopathologic Parameters Accompanying by Incidental Prostate Cancer
Objective: It is known that incidental prostate cancer (IPCa) can be seen in a low possibility for patients who were performed transurethral resection of the prostate (TURP) due to bladder outlet obstruction and/ or pro...
Should We Perform Thoracic Imaging for Every Patient with a Renal Mass?
Objective: Current guidelines for the management of renal mass recommend thoracic imaging for potential metastatic nodules. Small size of the renal mass can be associated with low metastatic potential, which might questi...
Prostate-specific Membrane Antigen-Based Nanomedicine Applications in the Diagnosis and Treatment of Prostate Cancer
Nanomedicine is a branch of nanotechnology that includes the development of nanostructures and nanoanalytical systems for various medical applications. The rapid development of nanomedicine offers new possibilities in ca...