Prediction of Distal Femoral Mechanical Strength Following Tumor Curettage and Cementation Using Quantitative Computed Tomography-based Finite Element Method
Journal Title: Majallah-i jarrāḥī-i ustukhvān va mafāṣil-i Īrān - Year 2018, Vol 16, Issue 3
Abstract
Background: Tumor curettage and cementation is a widely-used treatment of benign bone tumors in the distal femur. While postoperative fracture is a common complication, no criterion or biomechanical data is available to identify patients at high risk of fracture. Given the strong correlation between bone strength and its fracture risk, this study aimed to develop a non-invasive method to predict distal femoral strength following the surgery. Methods: 14 cadaveric human distal femora in which tumor surgery was mimicked by curettage and cementation (similar to the treatment of giant cell tumor in this region) were tested under compression force to measure bone strength. In addition, the 3D models of the specimens were created using quantitative computed tomography (QCT) images. Bone strength was measured with finite element analysis (FEA) in ABAQUS by applying loading conditions similar to the mechanical tests on the models. The accuracy and precision of the models in predicting bone strength were evaluated using paired t-tests and linear regression analyses. Results: No significant difference was observed between bone strengths predicted using FEA and the values measured in the laboratory via mechanical tests based on paired t-tests results (P>0.05). Moreover, regression analyses indicated a linear relationship between experimentally measured and FEA predicted bone strengths with a slope not different from 1. Conclusion: The results demonstrated the capability of QCT-based FEA in predicting bone strength in distal femur following tumor surgery. Therefore, the method can be employed to assess various features of bone-cement constructs with the hope of shedding light on the obscure aspects of the problem.
Authors and Affiliations
Azadeh Ghouchani, Gholamreza Rouhi, Mohammad Hosein Ebrahimzadeh
Keywords
Related Articles
- EP ID EP565371
- DOI -
- Views 46
- Downloads 0
Evaluation the effect of Pistacia atlantica hydro alcoholic extract with bone marrow- derived stem cells on induced knee osteoarthritis in rat
Background: Osteoarthritis is a progressive joint disease. Mastic fruit has antioxidant and anti-inflammatory properties. Bone marrow stem cells have the ability to differentiate into chondrocyte. The purpose of this stu...
Acrometastasis to Two Phalanges of a Single Phalanx and Tibia
Acrometastasis or metastasis distal to elbow and/or knee is a very rare event. A 31 y/o female, a known case of breast cancer for 3 years presented with a swollen 4th right finger. Radiographs and then biopsy showed sepa...
Prevalence and reason for removal of orthopaedic implants in one year
Background: Removal of implants used for fixation in orthopaedic cases is a fairly common procedure. There are varied views as to the need for removal of such implants on elective surgical schedules. There is no evidence...
Pain Management in Total Knee and Hip Arthroplasty
In recent years, the management and treatment of pain in surgery, especially the painful operation of hip and knee replacement, has been highly sought after by pain and orthopedic surgeons and therefore is of paramount i...
Control of Bacterial Infections after Knee Joint Replacement
Background: Knee joint replacement is an effective method to decrease pain and improve knee function in patients with advanced knee joint arthritis. However, there are some factors leading to the failure of the treatment...