PREDICTION OF MULTIPHASE ALTERNATIVE OF ACUTE DISSEMINATED ENCEPHALOMYELITIS COURSE DEVELOPMENT

Abstract

Prediction of development of the multi-phase alternative for the course inherent to acute disseminated encephalomyelitis (ADEM) is of great clinical importance, as it enables timely determination of the treatment tactics as well as volume of respective therapeutic interventions. This work is aimed at ascertaining the prognostic factors that determine the risk of development of the multi-phase course in disseminated encephalomyelitis. We have examined 101 patients with the diagnosis ADEM, namely: 28 men and 73 women in the age from 17 up to 53 years (average value 31.7±1.01years). To ascertain the prognostic meaning of clinic-paraclinic indices corresponding to patients with ADEM, we estimated the cumulative part of absence of relapses in the group of patients by using the Kaplan-Meyer method with estimating the Fisher criterion and using the most important clinic- paraclinic data. Development of the multiphase course in ADEM is reliably related to the following prognostic signs: changes in the neurologic status of patients with ADEM, degree of disability in accord with the EDSS scale as well as sizes of demyelination focuses determined using MRT. Criteria for congenial prediction in disease development with delayed appearance of ADEM relapses in the form of the multi-phase course are as follows: domination of motor impairments over coordinative impairments in neurological status, slight degree (in EDSS scale) of disability and small sizes (up to 4 mm) of demyelination focuses (MRT data). Our analysis of the main clinic-paraclinic indices obtained using the Kaplan-Meyer method indicates reliability of results and enables us to find a number of important prognostic criteria for appearance of the multiphase course in ADE

Authors and Affiliations

I. Lobanova.

Keywords

Related Articles

CLINICAL EVALUATION OF HAEMOSTASIS DISORDERS AT PREGNANT WOMAN WITH PATHOLOGICAL LEVEL OF ANTIPHPOSPHOLIPID ANTIBODIES AGGRAVATED BY MISCARRIAGE

Results of complex examination of immunological status and haemostasis at 30 pregnant women with threatened labor are considered. Antiphospholipid syndrome carry on hypercoagulation, decreasing of antithrombine III and p...

IMPLEMENTATION OF RECOMMENDATIONS ADAPTED REHABILITATION OF PATIENTS WITH MYOCARDIAL INFARCTION COMPLICATED HEART FAILURE

Application of the proposed rehabilitation activities has reduced the period of temporary disability in patients with group 2compared with 1 to 3,6 ± 0,8 days. The period of rehabilitation in patients with group 2 was mo...

IGG4-RELATED DISEASES – A NEW CLASSIFICATION UNIT IN RHEUMATOLOGY

This article presents the recent published data about the new classification unit in rheumatology – IgG4-related disease. It is demonstrated a pathogenic role IgG4, tumor necrosis factor ligand BAFF and APRIL, T and B ly...

EFFECT OF ANTIHYPERTENSIVE AGENTS ON THE ULTRASTRUCTURE OF THE MYOCARDIUM OF RATS SPONTANEOUSLY HYPERTENSION

It has been found out that hypertensive rats have substantial malfunction of contractile and energy cardiomyocyte apparatuses of predominantly destructive nature. Amlodipine decreases number of injured myofibrils, preven...

INVESTIGATION OF FUNCTIONAL PSYCHO- EMOTIONAL STATE OF CHILDREN WITH CHRONIC CHOLECYSTOCHOLANGITIS IN APPLICATION OF STANDARD AND COMBINED REGIMENS

Studies in included dynamic changes of emotional state of surveillance of 120 children with chronic cholecystocholangitis. Established that the use of standard therapy patients increased level of well-being in a better i...

Download PDF file
  • EP ID EP100374
  • DOI -
  • Views 91
  • Downloads 0

How To Cite

I. Lobanova. (2013). PREDICTION OF MULTIPHASE ALTERNATIVE OF ACUTE DISSEMINATED ENCEPHALOMYELITIS COURSE DEVELOPMENT. Ukrainian Scientific Medical Youth Journal / Український Науково-Медичний Молодіжний Журнал, 73(2), 37-42. https://europub.co.uk/articles/-A-100374