Prediction of Potential Lead Molecules through Systematic Integration of Multi-omics Datasets - A Mini-Review
Journal Title: International Journal of Current Research and Review - Year 2017, Vol 9, Issue 19
Abstract
Prediction of a novel or potential lead molecules for a therapeutic drug target without adverse effects is a challenging task in the drug designing, discovery, and development process. The systematic integration of multi-omics data from various data/knowledge bases through computational techniques enables to identify potential lead molecules and study the therapeutic properties. Over the last decades, several drug discoveries using multi-omics and huge dataset integration methods proven with successive results. In this paper, we present different types of computational approaches for prediction of potential lead molecules through the systems-level integration of multi-omics datasets.
Authors and Affiliations
Ashok Kumar T
Keywords
Related Articles
- EP ID EP607852
- DOI 10.7324/IJCRR.2017.9194
- Views 137
- Downloads 0
Multi-Functional Silver Nanoparticles for Drug Delivery: A Review
An operative management of complex physiochemical properties of drugs is vital for their effective cellular uptake and action. During the last decade, the complexity of drugs addressed in the state-of-the-art therapeutic...
Effect of Hydrochloric Acid (HCl) on Synthesis, Spectral and Thermal Properties of Triglycine Phosphate (TGP) Single Crystals
The effect of hydochloric acid (HCl) addition on the growth of triglycine phosphate (TGP) crystal has been studied from the aqueous solution by slow evaporation technique. Significant changes in the crystal size and morp...
Effect of Gestational Diabetes Mellitus on Macrosomia Infants
Aim: This study aims to explore fetal and maternal complications of macrosomia; and also to compare fetal characteristics of macrosomia infants of GDM and Non- GDM mothers. Methodology: This is a retrospective study, on...
Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study
Background: Molar incisor hypomineralization (MIH) describes the clinical picture of hypomineralization of systemic origin affecting one or more first permanent molar and incisors. Although the reported prevalence of MIH...
A Study on Occurrence of Two Rarest Coccoidal Cyanobacteria from India
Two species of one of the rare form of Cyanobacteria viz. Chlorogloeafritschii & Chlorogloeamicrocystoides was reported. The report is very significant from the point of impact that these two species being reported for t...