Predictors of outcome in non traumatic coma at tertiary care hospital, Latur, Maharashtra
Journal Title: MedPulse -International Medical Journal - Year 2015, Vol 2, Issue 12
Abstract
Introduction: Non traumatic or medical coma can result from wide range of primary etiologies and accounts for high morbidity and mortality. Coma ordinarily implies a poor prognosis and early prognostication is important for treatment decisions. The study was undertaken to study the factors associated with mortality in nontraumatic coma in a tertiary hospital in latur, Maharashtra. Materials and Methods: In this prospective observational study, Adults with clinically confirmed coma, Glasgow coma scale (GCS) score of ≤8, admitted consecutively to the emergency unit of a tertiary hospital over period of 2 years were consecutively recruited. Etiology of coma was determined on the basis of history, clinical examination, relevant laboratory and radiological investigations. Outcome, over one month was recorded. Functional outcome of the survivors was assessed with Glasgow Outcome Scale. Results: A total of 136 (84 males, 52 females) patients were recruited. Predominat etiologies identified were stroke followed by infections metabolic encephalopathy, poisoning. Whereas etiology was undetermined in 5.9% patients. Mortality was 46.3 %.. Low GCS score on admission, duration of coma, time lapsed between onset of coma and presentation to emergency unit age >50 years, abnormal blood pressure on admission and absent pupillary reflex were observed to be statistically significant predictors of outcome of non traumatic coma. Conclusion: Overall non traumatic coma has poor prognosis. age >50 years, abnormal blood pressure on admission, absent pupillary reflex Low GCS score on admission, duration of coma, time lapsed between onset of coma and presentation to emergency unit are important predictors of mortality of non traumatic coma.
Authors and Affiliations
S B Jagtap, S P Toshniwal, Imran Shaikh
Keywords
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